Effet de L'acide Caféoylshikimique des Racines du Palmier Dattier sur L'activité et la Production des Enzymes Hydrolytiques de <i>Fusarium oxysporum</i> f. sp. <i>albedinis</i>

Modafar, Cherkaoui El; Tantaoui, A.; Boustani, E. El

doi:10.1046/j.1439-0434.2000.00472.x

Cited by 18 publications

(3 citation statements)

References 30 publications

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“…A weak activity of M. oppositifolius isolates was recorded on yeasts with inhibition zone diameters between 10 and 18 mm compared to the reference drug (amphotericin B, 21-23 mm). Nevertheless, the elicited activity could be inherently attributed to the presence of antimicrobial secondary metabolites such as phenols, tannins, flavonoids, alkaloids, glycosides, anthraquinones, terpenoids and essential oils previously reported in M. oppositifolius (Gbedema et al, 2010;Herborne, 1976;Okwu and Okwu, 2004) either on an individual scale, or to their concerted contributions (Cowan, 1999;Latte and Kolodziej, 2000;Modafar et al, 2000;Charrouf and Guillaume, 2002). C. albicans was less susceptible than C. krusei to fraction G. Indeed, M. oppositifolius extracts previously showed varying degrees of in vitro antifungal activity against yeasts (Adekunle and Ikumapayi, 2006;Mosango, 2007).…”

Section: Discussionmentioning

confidence: 95%

Phytochemical analysis and antifungal property of Mallotus oppositifolius (Geiseler) Müll.Arg. (Euphorbiaceae)

Ngouana¹,

Fokou²,

Menkem³

et al. 2021

Int. J. Bio. Chem. Sci

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The emergence of resistant fungi to available drugs highlights the need for new antifungal drugs. The present study aimed to evaluate the antifungal activity of the isolated compounds, fractions and crude extract from the leaf of Mallotus oppositifolius (Geiseler) Müll. Arg. Three pure compounds labelled 1-3 were isolated from the methylene chloride / methanol (1/1) extract of the leaf of this plant using chromatography techniques. These compounds were identified using analytical spectroscopic methods as betulinic acid (1), quercetine (2) and quercitin (3). The crude extract, fractions and compounds were tested against pathogenic yeasts (Candida albicans, Candida glabrata, Candida krusei) and dermatophytes (Trichophyton rubrum, Trichophyton soudanense, Microsporum audouinii, Microsporum langeronii) using agar well diffusion and dilution methods. The safety of the crude extract was studied on Wistar rats according to the WHO guidelines. The minimal inhibitory concentration (MIC) values ranged from 48 to 781 μg/ml against yeasts for crude extract and fractions, and 1.86 to 25000 μg/ml against dermatophytes for pure compounds, fractions and crude extract. The antifungal activity of pure compounds was not determined against yeasts. The crude extract of leaf was found to be safe in rat at up to 12 g/kg. The results achieved supported the traditional use of Mallotus oppositifolius leaf for the treatment of fungal infections.Keywords: Mallotus oppositifolius, antifungal activity, safety, phytochemical screening.

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Section: Discussionmentioning

confidence: 95%

Phytochemical analysis and antifungal property of Mallotus oppositifolius (Geiseler) Müll.Arg. (Euphorbiaceae)

Ngouana¹,

Fokou²,

Menkem³

et al. 2021

Int. J. Bio. Chem. Sci

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“…The resistance mechanisms of date palm against this infection are few known; they are generally based on secondary metabolism pathways, particularly leading to phenolic compounds [3,4]; [5][6][7], reinforcement of the cell walls by the intensification of lignifications [7][8][9] and steroidal saponins [10,11].…”

Section: Introductionmentioning

confidence: 99%

Mobilization of trans-cinnamic acid, precursor of lignins in date palm roots over a compatible interaction with the pathogenic agent of bayoud disease, Fusarium oxysporum f. sp. albedinis

Boucenna-Mouzali¹,

Gaceb-Terrak²,

Kettout³

et al. 2021

J. Fundam and Appl Sci.

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Bayoud disease of date palm Phoenix dactylifera L. is the result of specific interactions established between this plant and Fusarium oxysporum f. sp. albedinis (F.o.a.). Facing this aggression, the host plant uses its constitutive preventive system and also defense mechanisms triggered by the pathogen. Our work is based on the identification of secondary metabolites produced during this confrontation in date palm roots. Our results show that during infection, susceptible cultivar accumulates considerable proportions of para-hydroxybenzoic acid. In soils infested by F.o.a., a significant decrease of para-hydroxybenzoic acid and an accumulation of para-hydroxycinnamic acid were observed in the roots of resistant cultivar. The analysis we realized shows that preferential orientation of the precursor “trans-cinnamic acid” of phenolic metabolism is activated in the root in contact with the causative agent of Bayoud. It also shows the presence of a greatest amount of lignin in resistant cultivar roots when compared with the susceptible ones.

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“…19,20 Suberin, lignin, and phenolics such as ferulic acid are all thought to play roles in strengthening both the primary cell wall and the middle lamellar pectin. [20][21][22][23][24][25][26][27] In the current work, intercellular adhesion strengthening in potato tuber parenchyma has been induced reproducibly by exposure to low pH acetic acid solutions under tissue culture conditions. The resulting tissues have been examined by magic angle spinning (MAS) solid-state 13 C nuclear magnetic resonance (NMR) spectroscopy, a powerful and widely used tool for comprehensive elucidation of the chemical structure of amorphous organic solid materials.…”

Section: Introductionmentioning

confidence: 99%

Magic-Angle Spinning NMR Studies of Cell Wall Bound Aromatic−Aliphatic Biopolyesters Associated with Strengthening of Intercellular Adhesion in Potato (Solanum tuberosum L.) Tuber Parenchyma

Vengadesan

Wang

et al. 2006

Biomacromolecules

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Intercellular adhesion strengthening, a phenomenon that compromises the texture and the edible quality of potatoes (Solanum tuberosum L.), has been induced reproducibly by exposure to low-pH acetic acid solutions under tissue culture conditions. The resulting parenchyma tissues have been examined by solid-state nuclear magnetic resonance (NMR) in order to characterize the biopolymer(s) thought to be associated with this syndrome. Cross polarization-magic angle spinning (CPMAS) (13)C NMR has been used to establish the presence of a polyphenol-suberin-like aromatic-aliphatic polyester within an abundant cell wall polysaccharide matrix in potato tubers that exhibit hardening due to strengthened intercellular adhesion. Dipolar dephasing and CP chemical shift anisotropy experiments suggest that the aromatic domain is composed primarily of guaiacyl and sinapyl groups. Two-dimensional wide-line separation experiments show that the biopolymer associated with parenchyma hardening contains rigid polysaccharide cell walls and mobile aliphatic long-chain fatty acids; (1)H spin diffusion experiments show that these flexible aliphatic chains are proximal to both the phenolics and a subpopulation of the cell wall polysaccharides. Finally, high-resolution MAS NMR of parenchyma samples swelled in DMSO in conjunction with two-dimensional through-bond and through-space NMR spectroscopy provides evidence for covalent linkages among the polysaccharide, phenolic, and aliphatic domains of the intercellular adhesion-strengthening biopolymer in potato parenchyma tissue.

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Effet de L'acide Caféoylshikimique des Racines du Palmier Dattier sur L'activité et la Production des Enzymes Hydrolytiques de Fusarium oxysporum f. sp. albedinis

Cited by 18 publications

References 30 publications

Phytochemical analysis and antifungal property of Mallotus oppositifolius (Geiseler) Müll.Arg. (Euphorbiaceae)

Phytochemical analysis and antifungal property of Mallotus oppositifolius (Geiseler) Müll.Arg. (Euphorbiaceae)

Mobilization of trans-cinnamic acid, precursor of lignins in date palm roots over a compatible interaction with the pathogenic agent of bayoud disease, Fusarium oxysporum f. sp. albedinis

Magic-Angle Spinning NMR Studies of Cell Wall Bound Aromatic−Aliphatic Biopolyesters Associated with Strengthening of Intercellular Adhesion in Potato (Solanum tuberosum L.) Tuber Parenchyma

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