“…The predominant targets of corticostriatal and thalamostriatal projections are the dendritic spines of the medium-sized spiny neurons (MSNs), the main neuronal cell-type and principal projection neuron of the striatum (Kemp and Powell, 1971a,b;Somogyi et al, 1981;Dubé et al, 1988;Xu et al, 1989;Smith and Bolam, 1990;Xu et al, 1991;Sadikot et al, 1992;Smith et al, 1994Smith et al, , 2004Bolam et al, 2000;Lacey et al, 2005;Raju et al, 2006Raju et al, , 2008Moss and Bolam, 2008).…”