1998
DOI: 10.1002/(sici)1099-1263(199803/04)18:2<143::aid-jat485>3.0.co;2-p
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Effects ofS-Adenosyl-L -methionine and interferon-α2b on liver damage induced by bile duct ligation in rats

Abstract: Interferon‐α2b (IFN) is known to prevent and to reverse experimental liver fibrosis and damage. S‐Adenosyl‐l‐methionine (SAM) is a well‐known hepatoprotective substance. The aim of the present work was to determine the effect of the administration of both drugs simultaneously to bile duct‐ligated rats. Administration of IFN (50 000 IU s.c.) and/or SAM (10 mg kg−1 i.m.) began 15 days after biliary obstruction and continued for a further 15 days. The liver was used for glycogen and collagen quantification. Bilir… Show more

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Cited by 11 publications
(1 citation statement)
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“…Over past decades, geologists have used several pretreatment procedures prior to isotopic analyses to eliminate allochthonous organic and inorganic particles attached to the sample shells. The techniques used to separate boron from organic matter have included ultraviolet irradiation; the use of organic‐matter‐specific resins, activated carbon, or hydrogen peroxide;15 and bleaching with sodium hypochlorite (NaClO) combined with sodium hydroxide (NaOH) 8, 16–18. None of these approaches has been completely satisfactory 12…”
mentioning
confidence: 99%
“…Over past decades, geologists have used several pretreatment procedures prior to isotopic analyses to eliminate allochthonous organic and inorganic particles attached to the sample shells. The techniques used to separate boron from organic matter have included ultraviolet irradiation; the use of organic‐matter‐specific resins, activated carbon, or hydrogen peroxide;15 and bleaching with sodium hypochlorite (NaClO) combined with sodium hydroxide (NaOH) 8, 16–18. None of these approaches has been completely satisfactory 12…”
mentioning
confidence: 99%