Effects of water-borne cadmium on plasma cortisol and glucose in the cichlid fish Oreochromis mossambicus

Pratap, H.B.; Bonga, S.E. Wendelaar

doi:10.1016/0742-8413(90)90124-r

Cited by 60 publications

(35 citation statements)

References 42 publications

(36 reference statements)

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“…The observed increase in the serum glucose level in Mugil cephalus L, exposed to lead in this study is in accord with report of some earlier workers. Similar increase in plasma glucose was also reported in Prochidolus lineatus exposed to lead [24] and in Oreochromis niloticus exposed to copper [25]. It has been widely reported that hyperglycaemia in fish arises due to the stimulation of catecholamines and corticosteroids [26].…”

Section: Discussionsupporting

confidence: 60%

Alterations in the Leucocytes and Serum Biochemistry in Grey Mu llet (Mugil cephalus L ,) Fingerlings Exposed to Sub lethal Doses of Lead for Different Exposure Periods

El-Shafei¹

2017

J Aquac Res Development

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Section: Discussionsupporting

confidence: 60%

Alterations in the Leucocytes and Serum Biochemistry in Grey Mu llet (Mugil cephalus L ,) Fingerlings Exposed to Sub lethal Doses of Lead for Different Exposure Periods

El-Shafei¹

2017

J Aquac Res Development

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“…The observed increase in the serum glucose level in Mugil Cephalus L, exposed to lead in this study is in accord with report of some earlier workers. Similar increase in plasma glucose was also reported in Prochidolus lineatus exposed to lead [24] and in Oreochromis niloticus exposed to copper [25]. It has been widely reported that hyperglycaemia in fish arises due to the stimulation of catecholamines and corticosteroids [26] .…”

Section: Discussionsupporting

confidence: 56%

Alterations in the Leucocytes and Serum Biochemistry in grey mullet (Mugil cephalus L,) fingerlings Exposed to Sub lethal doses of Lead for different exposure periods

El-Shafei¹

2017

IJBB

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Abstract:Grey Mullet Mugil cephalus L, fingerlings were chronically exposed to sub lethal concentrations of lead(Pb) (0.1 and 0.4 mg/L for twenty eight. The changes in the leucocytes and serum glucose, protein, and total cholesterol of the fish were determined every seven days in a renewable static bioassay system. At the end of the study, these parameters were significantly (p < 0.05) elevated in the Pb -exposed groups when compared with the control group. Showing a pronounced leuocytosis in the Pb-exposed fish. The magnitude of increase was influenced by increasing of exposure period and Pb concentration. The Pb exposed fish were significantly (p<0.05) hyperglycemic and hyperbcholesteremic. The serum glucose levels on the 7th day were 26.50 ± 2.12 g/dl and 30.50 ± 0.70 g/dl in the fish exposed to 0.1 and 0.4 mg Pb /L respectively. On the 28th day , the serum glucose concentrations were 52.50 ± 2.12 and 70.00 ± 2.83 g Pb /dl in the groups exposed to 0.1 and 0.4 mg Pb/L , respectively. The cholesterol concentration increased from 113.5±3.53 mg Pb /dl on day 7 to 208.0 ± 1.80 mg/dl on day 28 in the group exposed to 0.1mg Pb /L. When the fish was exposed to 0.4mg Pb /L lead acetate, the cholesterol concentration increased from 131.5 ±3.54 in the first week to 288± 5.19mg Pb /dl on 28th day of the study. The serum protein concentration was also significantly (p< 0.05) increased in the Pb -exposed groups when compared with the control group, it increased from 4.04±0.06mg Pb /dl on day 7 to 5.30±0.05 mg/dl on day 28 in the fish exposed to 0.1mgPb /L. When the fish treated with 0.4mg Pb /L , the serum protein increased from 4.45±0.37 mg/dl on day 7 to 6.18±0.19 mg Pb /dl on day 28, respectively. These changes are indicative of stress imposed on the fish by lead and could be used as indices of lead poisoning 165

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“…*Indicates significance difference from the control (p < 0.05). Several heavy metals have been reported to stimulate interrenal activity and plasma corticosteroid and glucose levels in fish (Pratap & Wendelaar Bonga, 1990). Hypersecretion of adrenalin and cortisol are considered primary stress responses.…”

Section: Discussionmentioning

confidence: 99%

Acute morphological and physiological effects of lead in the neotropical fish Prochilodus lineatus

et al. 2004

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The present study investigated lead effects on gill morphology, hematocrit, blood sodium, glucose, lipids, protein, and cholesterol of Prochilodus lineatus exposed to two sublethal lead concentrations for 96 h. Preliminary series of short-term static toxicity tests were run to determine LC 50 (96 h) of lead in P. lineatus, which was 95 mg Pb.L -1. Therefore, lead concentrations tested in the sublethal experiments were 24 and 71 mg Pb.L -1 , which correspond to 25% and 75% of the LC 50 (96 h), respectively. Gills of P. lineatus exposed to both lead concentrations during 96 h presented a higher occurrence of histopathological lesions such as epithelial lifting, hyperplasia, and lamellar aneurism. P. lineatus did not show significant alterations in hematocrit during exposure to both lead concentrations. Fish exposed to the highest lead concentration showed a significant decrease in Na + plasma concentration after 48 h, possibly reflecting a sodium influx rate decrease. P. lineatus exposed to both lead concentrations presented a "classical general adaptation syndrome to stress", as hyperglycemia associated with lowered lipids and proteins was reported. Stressresponse magnitude was dose-dependent. While the response to the lowest lead concentration might represent adaptation, the highest concentration seems to characterize exhaustion.Key words: lead, gill histopathology, Prochilodus lineatus, plasma sodium, stress response. , que correspondem a 25% e 75%, respectivamente, da CL 50 (96 h). As brânquias de P. lineatus expostos a ambas as concentrações de chumbo apresentaram maior incidência de lesões histopatológicas, como elevação epitelial, hiperplasia e aneurisma lamelar. P. lineatus não apresentou alterações significativas no hematócrito durante a exposição a ambas as concentrações de chumbo. Peixes expostos a 71 mg Pb.L -1 apresentaram decréscimo significativo do Na + plasmático após 48 h, o que pode estar se refletindo na redução das taxas de influxo desse íon. P. lineatus expostos a ambas as concentrações de chumbo apresentaram resposta clássica ao estresse, como verificado pela hiperglicemia associada ao decréscimo dos lipídeos e proteínas plasmáticas. A magnitude da resposta ao estresse foi dose-dependente. A resposta apresentada na concentração mais baixa representa um processo adaptativo, enquanto na maior concentração caracteriza a exaustão. RESUMOPalavras-chave: chumbo, histopatologia branquial, Prochilodus lineatus, sódio plasmático, resposta ao estresse.

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Effects of water-borne cadmium on plasma cortisol and glucose in the cichlid fish Oreochromis mossambicus

Cited by 60 publications

References 42 publications

Alterations in the Leucocytes and Serum Biochemistry in Grey Mu llet (Mugil cephalus L ,) Fingerlings Exposed to Sub lethal Doses of Lead for Different Exposure Periods

Alterations in the Leucocytes and Serum Biochemistry in Grey Mu llet (Mugil cephalus L ,) Fingerlings Exposed to Sub lethal Doses of Lead for Different Exposure Periods

Alterations in the Leucocytes and Serum Biochemistry in grey mullet (Mugil cephalus L,) fingerlings Exposed to Sub lethal doses of Lead for different exposure periods

Acute morphological and physiological effects of lead in the neotropical fish Prochilodus lineatus

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