Effects of vitamin C on the pharmacokinetics and pharmacodynamics of nimodipine in rats
Xian‐xin Meng,
Guan‐jun Nan,
Hao Hu
et al.
Abstract:In recent years, researchers have shown a growing interest in the interactions between different pharmaceutical agents. An intriguing instance lies in the possible interaction between nimodipine and vitamin C. To investigate the pharmacokinetic and pharmacodynamic effects of vitamin C on nimodipine in rats, rats were randomly divided into a nimodipine only group and a combination group (nimodipine + vitamin C). The two groups were given intragastric administration and nimodipine blood concentrations were deter… Show more
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