“…The intestinal barrier composed of intestinal epithelial cells, intestinal mucosa and intestinal flora blocks the entry of some chemicals. A complex intestinal organoid can fully reflect the impact of chemical poisons [118] on it and its toxic mechanism [119] . The combination of benzo [a] pyrene (B (a) P) and aged polystyrene microplastics (PSMPs) damaged the intestinal barrier [120] .…”