Effects of Various Intensities of X Radiation on Chromosomal Aberrations

Beatty, Alvin V.; Beatty, Jeanne W.; Collins, Cynthia S.

doi:10.1002/j.1537-2197.1956.tb10498.x

Cited by 13 publications

(3 citation statements)

References 24 publications

(12 reference statements)

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“…The effect of the 3-hour treatment in N2 is about the same as observed after radiation during the short N2 treatment. These results are not in agreement with Beatty et al (12,13,14). To determine whether the observed effect of anoxia actually resulted from oxygen starvation rather than from the induction of an unstable state which results in chromatid breaks in the presence of 02 during recovery (this might be thought of diagrammatica]ly as follows: chromosome + anoxia --* unstable state + oxygen reaction ~ breakage), lateral root tips were treated with (1) 3 hours of N~ followed by 2 hours of 02; (2) 3 hours of N2 followed by 2 hours of air; (3) 5 hours of N~.…”

Section: R E S U L T Scontrasting

confidence: 72%

“…Beatty et al (13) had previously observed that Tradescantia microspores treated for 400 minutes in He2 exhibited no aberrations but that this treatment in conjunction with radiation at low intensities (2 m~.~.) increased the radiation-induced damage to an appreciable extent over that induced following short exposures in helium.…”

Section: Discussionmentioning

confidence: 95%

“…Beatty et al (12,13), and Beatty and Beatty (14), reported observing, as a result of radiation, a pronounced increase in breakage frequency in Tradescantia microspore chromosomes when in helium for 400 minutes as against short exposures in helium. These experiments were repeated on Vicia root-tip cells and the results appear in Table I.…”

Section: R E S U L T Smentioning

confidence: 99%

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The Effect of Extended Anaerobic Treatments on the Chromosomes of Vicia faba

Merz

1959

The Journal of Cell Biology

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The effects of extended anaerobic treatments on Vicia faba lateral root-tip chromosomes were determined. It was observed that aberrations resulted from these treatments, and that the frequency varied from root to root as well as from experiment to experiment. It was suggested that the inconsistency observed might be due to variation in the abilities of different roots to produce energy via fermentation routes. If this were true, an inhibition of fermentation would result in a more consistent aberration frequency. A fermentation inhibitor, NaF, was used in combination with extended anaerobic treatments. The observed frequency of aberrations after the combined treatments was generally higher and considerably less variable. Although other hypotheses might account for the NaF effect, the hypothesis most compatible with the evidence is that the effect is due to energy deprivation. The experimental results are discussed in terms of the aforementioned effect and in terms of three alternative hypotheses for the production of chromosomal aberrations as a consequence of a lack of energy. It is concluded that damage might result from a build-up of normal cellular compounds to abnormally high concentrations which would act directly or indirectly on the chromosomes, from the breakdown of DNA as an energy source, or simply as a result of the fact that the chromosome needs energy to remain intact.

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Section: R E S U L T Scontrasting

confidence: 72%

Section: Discussionmentioning

confidence: 95%