Effects of using the GlobalFiler™ multiplex system on parent–child analyses of cases with single locus inconsistency

Ochiai, Eriko; Osawa, Motoki; Tamura, Tomonori; Minaguchi, Kiyoshi; Miyashita, Kazuyoshi; Matsushima, Yutaka; Kakimoto, Yu; Satoh, Fumiko

doi:10.1016/j.legalmed.2015.12.009

Cited by 7 publications

(1 citation statement)

References 21 publications

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“…Y-STR typing was performed using the AmpFLSTR Yfiler PCR Amplification Kit (Thermo Fisher Scientific Inc.), as described previously [19]. Briefly, after PCR amplification from 1 ng of DNA as the template, the product was separated using Genetic Analyzer 3500 and was typed on GeneMapper ID-X v1.4 (Thermo Fisher Scientific Inc.).…”

Section: Y-str Typingmentioning

confidence: 99%

Y chromosome analysis for common surnames in the Japanese male population

et al. 2021

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For many years of Japan's long history, Japanese surnames have been handed down patrilineally. This study investigated relations between major surnames and Y chromosomal polymorphism among the Japanese male population. To analyze genetic phylogeny in namesakes, the Y-single nucleotide polymorphism (SNP) plus Y-short tandem repeat (STR) approach was employed. A haplogroup based on SNPs and haplotypes at 17 STR loci were typed in 567 unrelated volunteers recruited in Kanagawa, Japan. Samples covered 27 common surnames such as Satoh and Suzuki, each name having 10-55 bearers. Significant difference was found for SNP haplogroup compositions and a multidimensional scaling plot using STR haplotypes in several surname groups. By contrast, these common surnames displayed wide diversity with phylogenetic networks, suggesting that no genetic drift event has occurred in their history. In all, 22 descent clusters were found, as judgcriteria ed by ad hoc of groups within five mutational steps in the 15 STR loci with the same haplogroup. The times of the most recent common ancestor ranged from 279 to over 2577 years. According to the approximate millennium span of Japanese surname history, descent criteria are expected to be reasonable for grouping within four step-neighbors. High heterogeneity of common surnames resembles that observed for England and Spain, but not for Ireland. Our results highlight that common Japanese surnames consist of descent clusters and many singletons, reflecting a mixture of long-term bearers and short-term bearers among the population. The genetic study of this population revealed characteristic features of Japanese surnames.

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Section: Y-str Typingmentioning

confidence: 99%