2018
DOI: 10.1007/s11695-018-3413-7
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Effects of Two Preoperatory Weight Loss Diets on Hepatic Volume, Metabolic Parameters, and Surgical Complications in Morbid Obese Bariatric Surgery Candidates: a Randomized Clinical Trial

Abstract: In subjects with morbid obesity undergoing bariatric surgery, compared to a LCD, a preoperative 21-day intervention with VLCD is more effective in terms of reducing total body weight but not in terms of reducing the liver volume. Both types of preoperative diets have similar effects on clinical biochemical parameters, rate of surgical complications, and hospital length stay.

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Cited by 37 publications
(75 citation statements)
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“…Andrianzen Vargas et al showed that LCD is insufficient in 60% of cases to achieve the intended 10% weight loss, while VLCD is able to achieve it in practically all patients [31]. However, a more recent study comparing the effect of VLCD and LCD before surgery showed that, although VLCD was more effective in reducing total body weight (5.8 vs. 4.2%), there were no differences in terms of liver volume reduction, with both diets having similar effects on biochemical parameters, rate of surgical complications, and hospital length stay [35]. More recently, very low-calorie ketogenic diet (VLCKD) has been proposed as a new effective and safe method for achieving effective preoperative weight loss.…”
Section: Vlcd and Vlckd Before Bs May Reduce Surgical Riskmentioning
confidence: 99%
“…Andrianzen Vargas et al showed that LCD is insufficient in 60% of cases to achieve the intended 10% weight loss, while VLCD is able to achieve it in practically all patients [31]. However, a more recent study comparing the effect of VLCD and LCD before surgery showed that, although VLCD was more effective in reducing total body weight (5.8 vs. 4.2%), there were no differences in terms of liver volume reduction, with both diets having similar effects on biochemical parameters, rate of surgical complications, and hospital length stay [35]. More recently, very low-calorie ketogenic diet (VLCKD) has been proposed as a new effective and safe method for achieving effective preoperative weight loss.…”
Section: Vlcd and Vlckd Before Bs May Reduce Surgical Riskmentioning
confidence: 99%
“…The above discussion regarding 5-10% weight loss in tier 3 should not be confused with the pre-operative weight loss achieved by the "liver shrinking" diet (which varies between LED, VLED and ketogenic diet) that has been shown to reduce liver volume before bariatric surgery and might have a favourable impact on wound healing, hospital stay and postsurgery complications [61][62][63][64].…”
Section: Selecting the Right Patient: Achieving 5-10% Weight Loss Befmentioning
confidence: 99%
“…Similar results can be found in a clinical trial by Gils Contreras et al where the liver volume was reduced by 15.6% after three weeks of VLCD. The reduction was directly related to the baseline BMI [26]. Generally, the highest decrease in liver volume seems to be achieved in the first two weeks of the diet [28,29].…”
Section: Diet and Microbiomementioning
confidence: 88%
“…Humans get approximately 10% of their daily energy supply from short-chain fatty acids (SCFAs) produced by the gut bacteria. SCFAs act not only as energy substrates for the host but also as signalling molecules thereby influencing energy intake and metabolism [25,26]. However, these SCFA profiles, along with butyrate-producing bacteria, are altered in obese individuals [27].…”
Section: The Intestinal Microbiome In Obesitymentioning
confidence: 99%
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