Effects of Triptorelin Versus Placebo on the Symptoms of Endometriosis

A self-administered questionnaire to measure the painful symptoms of endometriosis: Results of a modified DELPHI survey of patients and physicians

“…Measuring pain symptoms and Health-related quality of life (HrQol) in endometriosis patients was useful to assess treatment outcome in clinical trials including medical therapy, or surgery [4,5]. Various methods of pain assessment are available in the context of endometriosis, some of which have been validated with a high level of evidence.…”

Application of the nuclear factor-κB inhibitor BAY 11-7085 for the treatment of endometriosis: an in vitro study

“…GnRH agonists suppress the release of follicle-stimulating hormone and luteinizing hormone from the pituitary gland and inhibit ovarian steroidogenesis, resulting in a hypoestrogenic state that is suitable for the remission of the endometriotic lesions (5). However, treatments for endometriosis that aim to lower circulating estradiol concentrations can be used only for a limited time due to unacceptable side effects.…”

Management of the Pain Associated with Endometriosis: An Update of the Painful Problems

“…Of the five RCT studies (Dlugi et al 1990;Miller 1990;Fedele et al 1993;Bergqvist et al 1998;Ling 1999) on GnRH analogues eligible for this review (Table 2), one examined treatment of clinically suspected endometriosis (Ling 1999). The others explored minimal to mild endometriosis (Fedele et al 1993), minimal to severe endometriosis (Dlugi et al 1990;Bergqvist et al 1998), or unclassified endometriosis (Miller 1990).…”

“…The others explored minimal to mild endometriosis (Fedele et al 1993), minimal to severe endometriosis (Dlugi et al 1990;Bergqvist et al 1998), or unclassified endometriosis (Miller 1990). …”

“…for minimal to severe (Dlugi et al 1990;Bergqvist et al 1998) or unclassified endometriosis (Miller 1990). While GnRH analogues significantly reduced pain, the effects of GnRH analogues on dyspareunia were not consistent.…”