Effects of Triptolide on Cell Viability, Secretion of Inflammatory Cytokines, and Gene Expression of Severe Coronavirus Disease 2019(COVID-19)Pseudovirus Cell Model
Abstract:Background: Acute respiratory distress syndrome (ARDS), which is caused by severe immune cell response and associated alveolar inflammation, is also a critical complication in hospitalized patients with COVID-19. Triptolide is a powerful anti-inflammatory and immunosuppressive drug and is proved to help relieve the inflammation of ARDS. However, its anti-inflammatory effect on COVID-19 patients with ARDS complications remains uncertain. Methods: In this study, human normal lung epithelial cells (BEAS-2B), the … Show more
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