Abstract:Multiglycosides of Tripterygium wilfordii (GTW) have been found to exhibit reversible antifertility effects through complex mechanisms. The positive expression of sex hormones and receptors in Leydig cells were investigated following GTW treatment to determine the impact of GTW on male mandarin vole (Microtus mandarinus) fertility. Compared to the control group, body weight, testis and epididymis weight were not affected by GTW, but the number of sperm sharply declined. There were significant decreases in the … Show more
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