Effects of treadmill exercise on the timing of the heart and arterial sounds, and the slope of the brachial arterial pulse wave

Inagaki, Yoshiaki; Wassermil, Mendel; Rodbard, Simon

doi:10.1016/s0002-8703(76)80108-1

Cited by 5 publications

(2 citation statements)

References 14 publications

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“…The present study provides a data-base, upon which we may interpret these noninvasive measurements in the context of catheterization data, and utilize them in the clinical decision regarding the need for catheterization. Further, these data supplement those recently obtained, to examine the use of Sphygmo-Recording under conditions of exercise (23), exogenous catecholamines (24), alterations of thyroid status (25), effects of cardiac pacemakers (26), and of age and posture (27). Collectively, these studies provide a basis for evaluating the clinical utility of quantitation of pulse wave contour and timing.…”

Section: Discussionsupporting

confidence: 57%

Aortic and Brachial Pulse Wave Contour and Timing in Aortic Valve Disease

Hasegawa¹,

Rodbard²

1980

Cardiology

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The arrival time (QK_d) and contour (ΔP/Δt) of the brachial arterial pressure wave was recorded noninvasively by Sphygmo-Recording, and was correlated with clinical and catheterization data for 23 patients with aortic stenosis, aortic regurgitation, or combined valvular disease. The mean normal values in 57 healthy subjects were 203 msec for QK_d and 0.48 mm Hg msec^-1 for ΔP/Δt. In 9 cases of documented aortic stenosis, mean QK_d was prolonged (240 msec), and the mean ΔP/Δt of the brachial pressure wave was decreased (0.25 mm Hg msec^-1). In 7 patients with aortic regurgitation, QK_d tended to be shorter than normal (182 msec) and the upstroke exhibited a steeper slope (1.0 mm Hg msec^-1). Patients with combined aortic stenosis and regurgitation showed a QK_d in the normal range, and the slope of the arterial upstroke was also normal. QK_d and brachial arterial ΔP/Δt obtained noninvasively show a systematic relationship with data from catheterization studies; e.g. the calculated aortic valve orifice; the interval between peak ventricular and aortic pressures ΔP/Δt in the ascending aorta, and the ratio of aortic ΔP/Δt to that in the left ventricle. The indices based on the Korotkoff sounds did not correlate well with cardiac output, cardiac index, left ventricular ejection time or left ventricular end-diastolic pressure. After surgical placement of prosthetic aortic valves in 10 patients with aortic insufficiency, the QKd and ΔP/Δt returned into the normal range, or were slightly prolonged. Thus, the Sphygmo-Recorder provides a useful approach to cardiac evaluation both pre- and postoperatively.

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Section: Discussionsupporting

confidence: 57%

Aortic and Brachial Pulse Wave Contour and Timing in Aortic Valve Disease

Hasegawa¹,

Rodbard²

1980

Cardiology

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“…Since in an aortic s tenosi s most of the energy of the wave is in the lower harmonics, amplif ica ti on in the brachial artery, but not in the descending aorta, might be expected. Inagaki et al (1976) studied the effects of treadmill exercise on the slope of the brachial arterial pulse wave along with other cardiac parameters, and these studies provide a baseline for analysis of patients with cardiovascular disease. Millington and Record (1977) measured the radial arterial pulse under clinical conditions.…”

mentioning

confidence: 99%

Computer simulation of blood flow in the human arm

Balar

Rogge

Young

1989

Journal of Biomechanics

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This paper considers a finite element method to characterize blood flow in the human arm arteries. A set of different pressure waveforms, which represent normal and diseased heart pulses, is used for the proximal boundary conditions, and a modified Windkessel model is used for the distal arterial boundary conditions. A comparison of the distal pressure and flow waveforms, for each different proximal pressure, is made to determine whether such waveforms are significantly altered from normal waveforms. The results show that the distal pressure and/or flow waveforms in certain cases are sufficiently different to be possibly used as a diagnostic indicator of an abnormal heart condition. Also considered is the effect of stenosis, change of compliance, and dilatation of the distal beds on the pressure and flow waveforms. A stenosis which has an area reduction of greater than approximately 75% is found to significantly alter both the distal pressure and flow waveforms. Changes in arterial compliance, however, do not strongly influence the waveforms. Dilatation of distal vascular beds is simulated by reducing the lumped resistance of these beds, and this reduction increases mean flow and decreases mean distal pressure, but has little effect on the basic shape of either the pressure or flow waveform.

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