Study Objective: Pain is a sensory and emotional experience shown by the patient as a response to the damage of the skin tissue or muscle. In fact, it is usually found that diabetic patients who experience pain during wound care treatment can not be handled properly. The purpose of this study is to find out the effect of TENS intervention towards the level of pain in DM patients with peripheral neuropathy in diabetic foot ulcer treatment. Design: Random control trial (RCT) Method and Measurements: 28 respondents which were divided into 14 interventions and 14 control groups. Respondents' pain was assessed before and after the intervention of TENS for 15 minutes with the electrical frequency of 100 Hz using Numeric Rating Scale tools. Statistic test: statistical test was conducted using independent T test and Paired T test. Results: There is a difference in the level of pain in the intervention group and control groups with P = 0.000. Intervention of TENS for 15 minutes with a frequency of 100 Hz effectively reduces the pain level of the patients with diabetes mellitus with with peripheral neuropathy in diabetic foot ulcer treatment is done with a P value of <0.05. Conclusions: TENS effectively reduces pain in diabetic patients with peripheral neuropathy in diabetic foot ulcer treatment.