Effects of tramadol with tiletamine/zolazepam-xylazine as anaesthesia in cats

Li, Lin; Dong, Jing; Lu, Dezhang; Jiang, Sheng; Lin, Dongqi; Fan, Honggang

doi:10.2754/avb201382020219

Cited by 2 publications

(3 citation statements)

References 9 publications

(8 reference statements)

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“…Under normal circumstances, ketamine has few cardiopulmonary side effects; it does not inhibit the cardiovascular or respiratory system and has significant analgesic effect (3,7,14). Tramadol caused no significant additional respiratory depressant effect in cats (11). Our results showed that RR and SpO 2 in all treatments were not changed significantly compared with baseline, and the changes in RR and SpO 2 remained within clinically acceptable limits in all period of anesthesia.…”

Section: Tab 2 Mean ± Sd Values For Physiological Parameters Evaluated In Cats Anaesthetized With Two Combinations Of Anaesthetic Drugsmentioning

confidence: 50%

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Comparison of the anesthesia effects of ketamine, dexmedetomidine and tiletamine-zolazepam with or without tramadol in cats

Liang¹,

Wang²,

Li³

et al. 2021

Medycyna Weterynaryjna

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This study investigated the analgesia effects of intramuscular injection of ketamine, dexmedetomidine and tiletamine-zolazepam combined with tramadol (KDZT) and compared the efficacy of this combination with that of ketamine, dexmedetomidine and tiletamine-zolazepam (KDZ) in Chinese local mongrel cats. Ten cats were tested twice as a comparison between the two groups, and the interval between the two groups was more than a week. The animals received ketamine (10 mg/kg), dexmedetomidine (10 μg/kg) and zoletil (5 mg/kg) combined with or without tramadol (2 mg/kg) for anesthesia in separate tests. Heart rate, respiration rate, non-invasive systolic pressure, hemoglobin oxygen saturation, rectal temperature, subjective pain scores and venous blood-gas were measured simultaneously. The induction time, recovery time of the righting reflex, standing and walking, the time during the anesthesia period were recorded. Cardiopulmonary variables changed after injection, some of which were significantly different from baselines before anesthesia induction. Values regarding blood gas changed after intramuscular administration, and significant differences were found between two groups at one of the timepoints. Both KDZT and KDZ provided adequate analgesia in cats. The induction period of two anesthetic mixtures was within 1-3 min and could effectively maintain anesthesia for 75-175 min. The change of physiological parameters remained within a biologically acceptable range and was not significantly different between the two groups. The use of KDZT resulted in better anesthesia, with shorter anesthesia induction period and longer anesthesia period compared with KDZ. No side effects were observed, no rescue analgesic was required.

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Section: Tab 2 Mean ± Sd Values For Physiological Parameters Evaluated In Cats Anaesthetized With Two Combinations Of Anaesthetic Drugsmentioning

confidence: 50%

“…However, this degree of decline does not adversely affect the body. It has been reported that tramadol has no significant cardiovascular inhibitory effect on cats (11). Therefore, the effects of KDZT and KDZ on the heart can be ignored.…”

Section: Resultsmentioning

confidence: 99%

Comparison of the anesthesia effects of ketamine, dexmedetomidine and tiletamine-zolazepam with or without tramadol in cats

Liang¹,

Wang²,

Li³

et al. 2021

Medycyna Weterynaryjna

Self Cite

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“…Therefore, considering the ease of administration of medications in the case of cats and the comfort of the animal with respect to handling and environment, intramuscular injection of Tiletamine-zolazepam combination @ 8 mg/kg could be recommended as an excellent inducing agent providing quick rapid and smooth induction of anaesthesia in cats allowing easy intubation Fig 1. The effect of an inducing agent over skeletal muscle relaxation was based on a modified scale score given by Li et al (2013) which from 0 to 3, where score 0 being resistant to anaesthetic and 3 representing the most profound relaxation of muscles. The mean±S.E score for muscle relaxation was 2.6±0.14 in group A and 2.4±0.14 in group B with the cat exhibiting profound jaw relaxation and easy intubation.…”

Section: Resultsmentioning

confidence: 99%

Comparative Study on the Anaesthetic Effect of Tiletamine-zolazepam and Propofol as an Induction Agent for Conventional and Endoscopic Abdominal Surgeries in Domestic Cats

Chauhan¹,

Pant²,

Khandekar³

et al. 2023

IJAR

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Background: Felines have higher metabolic and heart rates than canines and therefore are considered to be the delicate subjects for anaesthesia and pain management. Major surgeries in felines require balanced anaesthesia with smooth and fast induction, longer duration of action and faster and excitement free recovery. Methods: The study was conducted on 24 clinical cases of cats, subjected to conventional and endoscopic surgeries for abdominal affections, premedicated with atropine and dexamethasone at the rate of 0.04 and 0.2 mg/kg body weight to assess the anaesthetic effect of tiletamine-zolazepam combination at the rate of 8mg/kg body weight IM in group A (n=12) and propofol @ 8 mg/kg body weight IV in group B (n=12) respectively as inducing agent to isoflurane maintained anaesthesia. Result: The mean induction time were 421.9±69.47 seconds (7.03±1.16 minutes) in group A and 56.2±0.43 seconds (0.94±0.01 minute) in group B. In both the groups quality of induction was smooth with rapid loss of all reflexes allowing easy intubation. A significant drop in rectal temperature at 15 min post induction with minimal alterations in heart rate, respiration rate and saturated oxygen level were observed. The mean time of recovery recorded were 75.91±8.1 minutes in group A and 88.2±10.2 minutes in group B. Smooth, rapid and good quality recovery was observed in both the anaesthetic groups; however, propofol-induced transitory hypothermia and shivering, lowered the quality of recovery in group B. All the physiological and hematological parameters were in normal limits.

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Effects of tramadol with tiletamine/zolazepam-xylazine as anaesthesia in cats

Cited by 2 publications

References 9 publications

Comparison of the anesthesia effects of ketamine, dexmedetomidine and tiletamine-zolazepam with or without tramadol in cats

Comparison of the anesthesia effects of ketamine, dexmedetomidine and tiletamine-zolazepam with or without tramadol in cats

Comparative Study on the Anaesthetic Effect of Tiletamine-zolazepam and Propofol as an Induction Agent for Conventional and Endoscopic Abdominal Surgeries in Domestic Cats

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