Effects of Thyroxin and Domperidone on Oocyte Maturation and Spawning Performances in the Rabbit Fish, Siganus guttatus

Abstract

Thyroxin (T4) is proven to have various functions in fish reproduction. In this study, we investigated oocyte maturation and spawning performance in the rabbit fish, Siganus guttatus, orally exposed to different doses of T4 (0.05, 0.25, and 0.5 mg/kg fish) during vitellogenesis. No statistically significant differences of reproductive characteristics were observed among the treatments. However, the group that was exposed to the dose of 0.5 mg/kg spawned after receiving a hormone injection. The findings suggest that feeding T4 during vitellogenesis did not advance oocyte maturation, but probably could induce spawning in rabbit fish. In a separate experiment, we investigated the effects of orally administered domperidone (DOM) on reproductive performances of the female rabbit fish. The study showed that oral administration of DOM during the early stages of the reproductive cycle had no significant effects on oocyte maturation and spawning performance. Overall, these findings suggest that DOM may not be needed for the induction of maturation and spawning of this species under aquaculture conditions. These practical investigations were conducted with a view to attempt reducing drug use, production costs, and support sustainable aquaculture.

Dopamine receptor agonist bromocriptine restrains the follicular development, hatchling success and puberty in Gambusia affinis

“…Linard et al (1995) and Saligaut et al (1999) (Sukumasavin, Sakulthong, & Sangthong, 2000) and in the crucian carp C. carassius (Cejko & Kucharczyk, 2015) substantiating the inhibitory role for DA. However, treatment with DA antagonist domperidone during early stages of reproductive cycle did not induce oocyte maturation and spawning in the rabbitfish Siganus guttatus (Hung & Hoang, 2016). These results suggest that the action of DA might be dependent on the stage of reproductive cycle in fish.…”

“…In teleosts, the ovarian activity is synchronized by the hormones produced by the BPG-axis (Nagahama, 1997 & Chang, 1986), the tilapia O. mossambicus (Yaron et al, 2003) and the zebra fish Danio rerio (Fontaine et al, 2013). However, treatment with DA antagonist domperidone during early stages of reproductive cycle did not induce oocyte maturation and spawning in the rabbitfish Siganus guttatus (Hung & Hoang, 2016). However, treatment with DA antagonist domperidone during early stages of reproductive cycle did not induce oocyte maturation and spawning in the rabbitfish Siganus guttatus (Hung & Hoang, 2016).…”

Gonadal Development and Associated Changes in Estradiol, Thyroid Hormones, and Sex-Related Genes During Different Growth Stages in Cultured Female Rainbow Trout (Oncorhynchus Mykiss) in Yunnan

“…Similarly, a recent study showed that the treatment to female gold sh (Carassius auratus) with T 3 resulted in an increase of VTG [9]. In contrast, rabbit sh (Siganus guttatus) fed T 4 during vitellogenesis did not advance oocyte maturation, but could induce spawning [23]. Moreover, in female S. trutta from a wild strain, the increase in plasma THs around the time of ovulation had an in uence on nal maturation of oocytes, while the absence of any appreciable change in pro le of T 4 indicated that the increase of THs are not necessary for ovarian maturation in cultured strain [12].…”

Effects of human chorionic gonadotropin and gonadotropin releasing hormone analogue on plasma steroid hormones and spawning performances in golden rabbitfish Siganus guttatus

“…Gonadotropins such as follicle-stimulating hormone (FSH) and luteinizing hormones (LH) regulate the biosynthesis of sex steroids that subsequently control the processes of sexual behavior and spermation/ovulation (Nagahama & Yamashita, 2008;Schulz et al, 2010;Zohar, Munoz-Cueto, Elizur, & Kah, 2010). hCG and D-Ala 6 , Pro 9 -Net-mGnRH are exogenous hormones that have been used separately or in combination for fish reproduction in many parts of Asia (Ayson, 1991;Komatsu, Bhandari, Kobayashi, Nakamura, & Nakamura, 2006;Marte, 1989;Pham & Le, 2016;Pham, Nguyen, Nguyen, & Arukwe, 2010). These exogenous hormones have been shown to improve maturation, ovulation and spawning performance in both wild and cultured fish species (Pham et al, 2010;Rahman, Takemura, & Takano, 2002;Zadmajid, 2016;Zadmajid, Bashiri, Sharafi, & Butts, 2018).…”