Effects of thyroid hormones modify the association between pre-pregnancy obesity and GDM: evidence from a mediation analysis
Xialidan Alifu,
Zexin Chen,
Yan Zhuang
et al.
Abstract:ObjectiveConflicting associations have been noted between thyroid function and gestational diabetes mellitus (GDM), with indications that pre-pregnancy BMI might influence these relationships. This study aims to examine the effect of thyroid hormone indices and their mediation role on the risk of GDM.MethodsPregnant women in our study were recruited from the Zhoushan Pregnant Women Cohort, Zhejiang Province, China. Participants who had their first prenatal follow-up and measured thyroid biomarkers in the first… Show more
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