“…Investigations in several laboratories have revealed that factors (hormones) from the epithelium in the thymus are involved in T-cell maturation. 324 H. FRIEDMAN and S. SPECTER Experimental models using Moloney sarcoma virus (ZISBLATT et al 1970) and virus-associated leukemia in AKR mice (BARKER et al 1979) demonstrated antiviral effects of tbymosin. ZAIZOV et al (1979) treated children with immunosuppression, lymphoproliferative malignancy, and generalized varicella with their thymic hormone factor.…”