Under global change scenarios, multistress
conditions may occur
regularly and require adaptation. However, the adaptation to one stressor
might be associated with the increased sensitivity to another stressor.
Here, we investigated the ecological consequences of such trade-off
under multiple stress. We compared the pesticide tolerance of the
crustacean Gammarus pulex from agricultural
streams with populations from reference streams. Under optimum temperature, G. pulex from agricultural streams were considerably
more tolerant to pesticides as compared to the reference populations.
Here, we assume that the increased tolerance in agricultural populations
is the combination of acclimation, epigenetic effect, and genetic
evolution. After experimental pre-exposure to very low concentration
(LC50/1000), reference populations showed increased pesticide
tolerance. In contrast, pre-exposure did not further increase the
tolerance of agricultural populations. Moreover, these populations
were more sensitive to elevated temperature alone due to the hypothesized
fitness cost of genetic adaptation to pesticides. However, both reference
and agricultural populations showed a similar tolerance to the combined
stress of pesticides and warming due to stronger synergistic effects
in adapted populations. As a result, pesticide adaptation loses its
advantage. The combined effect was predicted well using the stress
addition model, developed for predicting the synergistic interaction
of independent stressors. We conclude that under multistress conditions,
adaptation to pesticides reduces the general stress capacity of individuals
and trade-off processes increase the sensitivity to additional stressors.
This causes strong synergistic effects of additional stressors on
pesticide-adapted individuals.