Effects of the catch-relaxing peptide on molluscan muscles

Hirata, T.; Kubota, I.; Imada, M.; Muneoka, Yojiro; Kobayashi, Makoto

doi:10.1016/0742-8413(89)90055-8

Cited by 14 publications

(6 citation statements)

References 20 publications

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“…The principal cardioexcitatory and cardioinhibitory transmitters in molluscan hearts are thought to be, in general, 5-hydroxytrypamine (5-HT) and acetylcholine (ACh), respectively (Stefano 1990). In addition, the neuropeptide FMRF-amide (phenylalanine-methionine-arginine-phenylalanine-NH2) and catch-relaxing peptide may also be important in regulating cardiac activity in Mytilus spp (Painter and Greenberg 1982;Hirata et al 1989).…”

Section: Discussionmentioning

confidence: 98%

Automated interpulse-duration assessment (AIDA): a new technique for detecting disturbances in cardiac activity in selected macroinvertebrates

et al. 1996

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An Automated Interpulse Duration Assessment system (AIDA) is described which permits detection of irregularities in cardiac rhythms in selected invertebrates. The sensitivity of AIDA was demonstrated by its ability to detect handling stress in mussels (Mytilus edulis) that was not evident when measuring heart rate alone. Changes in cardiac activity patterns of crabs (Carcinus maenas) held in the laboratory for up to 10 wk was also examined using the new technique. The frequency distribution of interpulse duration changed significantly as the nutritional state changed. Potential applications of the AIDA system are discussed.

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Section: Discussionmentioning

confidence: 98%

Automated interpulse-duration assessment (AIDA): a new technique for detecting disturbances in cardiac activity in selected macroinvertebrates

et al. 1996

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“…The actions of myomodulins on the feeding muscles are also generally inhibitory. For example, the radula muscles of Fusinus and Rapana are inhibited by CARP (Fujiwara-Sakata et al, 1991), and myomodulin itself was shown to inhibit contractility of the radula muscle in Fusinus (Hirata et al, 1989). In contrast, in the Aplysia accessory radula closer (ARC) muscle, both myomodulin A and B enhance contractions (Cropper et al, 1991).…”

mentioning

confidence: 99%

Neuropeptides myomodulin, small cardioactive peptide, and buccalin in the central nervous system of Lymnaea stagnalis: Purification, immunoreactivity, and artifacts

Santama

Wheeler

Burke

et al. 1994

J of Comparative Neurology

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The neuropeptides myomodulin, small cardioactive peptide (SCP), and buccalin are widely distributed in the phylum Mollusca and have important physiological functions. Here, we describe the detailed distribution of each class of peptide in the central nervous system (CNS) of the snail Lymnaea stagnalis by the use of immunocytochemical techniques combined with dye-marking of electrophysiologically identified neurons. We report the isolation and structural characterization of a Lymnaea myomodulin, PMSMLRLamide, identical to myomodulin A of Aplysia californica. Myomodulin immunoreactivity was localized in all 11 ganglia, in their connectives, and in peripheral nerves. In many cases, myomodulin immunoreactivity appeared localized in neuronal clusters expressing FMRFamide-like peptides, but also in a large number of additional neurons. Double-labelling experiments demonstrated myomodulin immunoreactivity in the visceral white interneuron, involved in regulation of cardiorespiration. SCP-like immunoreactivity also appeared in all ganglia, and double-labelling experiments revealed that in many locations it was specifically associated with clusters expressing distinct exons of the FMRFamide gene that are differentially expressed in the CNS. Characterization of the two types of SCP-antisera used in this study, however, suggested that they cross-reacted with both FMRFamide and N-terminally extended FMRFamide-like peptides. Selective preadsorption with these cross-reacting peptides resulted in elimination of the widespread staining and retention of bona fide SCP immunoreactivity in the buccal and pedal ganglia only. Buccalin immunoreactivity was limited to the buccal and pedal ganglia. It did not coincide with the distribution of either myomodulin or SCP. Most immunoreactive clusters were found in the pedal ganglia.

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“…Thus, to test whether the catch-like state of the papillae is likely to follow the same mechanism as the catch of bivalve abductors, we first focused on the active compounds that control them. Acetylcholine has been previously demonstrated to excite bivalve catch muscles (Ishii et al, 1986; Hirata et al, 1989; Siegman et al, 1998), and FMRFamide has been demonstrated to induce contraction in the anterior byssus retractor muscle, a catch muscle of Mytilus (Hirata et al, 1989). It is therefore exciting that we found papillary muscles to be very sensitive to FMRFamide and Acetylcholine, in addition to L-glutamate, which drives a fast skin response.…”

Section: Discussionmentioning

confidence: 99%

Neural Control of Dynamic 3-Dimensional Skin Papillae for Cuttlefish Camouflage

et al. 2018

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SummaryThe color and pattern changing abilities of octopus, squid, and cuttlefish via chromatophore neuromuscular organs are unparalleled. Cuttlefish and octopuses also have a unique muscular hydrostat system in their skin. When this system is expressed, dermal bumps called papillae disrupt body shape and imitate the fine texture of surrounding objects, yet the control system is unknown. Here we report for papillae: (1) the motoneurons and the neurotransmitters that control activation and relaxation, (2) a physiologically fast expression and retraction system, and (3) a complex of smooth and striated muscles that enables long-term expression of papillae through sustained tension in the absence of neural input. The neural circuits controlling acute shape-shifting skin papillae in cuttlefish show homology to the iridescence circuits in squids. The sustained tension in papillary muscles for long-term camouflage utilizes muscle heterogeneity and points toward the existence of a “catch-like” mechanism that would reduce the necessary energy expenditure.

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Effects of the catch-relaxing peptide on molluscan muscles

Cited by 14 publications

References 20 publications

Automated interpulse-duration assessment (AIDA): a new technique for detecting disturbances in cardiac activity in selected macroinvertebrates

Automated interpulse-duration assessment (AIDA): a new technique for detecting disturbances in cardiac activity in selected macroinvertebrates

Neuropeptides myomodulin, small cardioactive peptide, and buccalin in the central nervous system of Lymnaea stagnalis: Purification, immunoreactivity, and artifacts

Neural Control of Dynamic 3-Dimensional Skin Papillae for Cuttlefish Camouflage

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