Effects of the Aqueous Extract ofEremomastax speciosa(Acanthaceae) on Sexual Behavior in Normal Male Rats

Abstract

Objective. We studied prosexual effects of Eremomastax speciosa aqueous extract in male adult rats. Materials and Methods. 100 and 500 mg/kg of extract were administered orally (days 0, 1, 4, 7, 14, and 28 (posttreatment)). The sexual behavior of rats receiving a single dose (500 mg/kg) was also evaluated after pretreatment with Lω-NAME (10 mg/kg), haloperidol (1 mg/kg), or atropine (5 mg/kg). Controls received distilled water or testosterone enanthate (20 mg/kg/day/3 days (s.c.) before the test). Results. The extract (days 1–14) had no significant effect on mount, intromission, and ejaculation frequencies but on day 28 (14 days after treatment), it increased frequency of mounts and intromissions at 500 mg/kg. Mount, intromission, and ejaculation latencies reduced and postejaculatory intervals decreased but the effect did not persist 2 weeks after treatment. Extract prosex effects were greatly reduced by atropine and completely abolished by haloperidol, while Lω-NAME increased mount latency and potentiated extract effect on intromission and ejaculation latencies. Conclusion. In summary, E. speciosa extract can have positive effects on male sexual motivation and performance when administered for two weeks at the dose of 500 mg/kg. The effects (dopaminergic and/or cholinergic dependent) tend to appear during the posttreatment period.

Aphrodisiac properties of Aquilaria malaccensis leaves aqueous extract in ICR mice

“…In this way, the decrease in the mount and intromission latencies was the positive result for the extract which might imply stimulation of sexual motivation and arousability. It may also be the sign of boosted sexual appetitive behaviour in experimental animals which further supports the sexual improvement effect of the plant extract [38,39]. Contrary results were obtained from the present study because AEAM was lack of aphrodisiac properties.…”

“…Nil values were recorded on intromission frequency and intromission latency in all groups because the mice being passive and sleepy starting from day 7 until the end of observation period (day 21) especially the treated mice groups that received the crude extract. Generally, mount and intromission latencies were used as indicators of sexual motivation [38]. However, they also claimed that ML and IL are inversely proportional to sexual motivation.…”

In vivo effects of Rauvolfia vomitoria ( Apocynaceae ) ethanolic extract on sexual performance and reproductive activity in male rats

“…Approximately 15% of couples worldwide are affected by infertility, amounting to 48.5 million couples (Agarwal, Mulgund, Hamada, & Chyatte, ). Although it is not possible to estimate an impartial prevalence of male infertility, the male reproductive ability was reported to be deficient in approximately 50% of infertile couples (Abedi, Parviz, Karimian, & Sadeghipour Rodsari, ; Nchegang et al, ). Nowadays, sexual dysfunction is reported to be one of the most common diseases more especially among the individuals having an age range of 40–70 years (Bansode, Rajendran, & Singh, ).…”

Alkaloid extracts from Bitter leaf ( Vernonia amygdalina ) and Black nightshade ( Solanum nigrum ) inhibit phosphodiesterase‐5, arginase activities and oxidative stress in rats penile tissue

“…Other phytoconstituents reportedly present in the vegetables include sesquiterpenes, flavonoids, phenolic acids, and alkaloids among others (Eleazu et al, ). Alkaloids are one of the readily available antioxidants found in bitter plants (Nchegang et al, ). In view of the foregoing, this study sought to provide information on possible erectogenic potential of alkaloids extracted from Black nightshade ( Solanum nigrum ) and Bitter leaf ( Vernonia amygdalina ) as alternative therapeutic agents for managing erectile dysfunction.…”

“…Alkaloids are one of the readily available antioxidants found in bitter plants (Nchegang et al, 2016). In view of the foregoing, this study sought to provide information on possible erectogenic potential of alkaloids extracted from Black nightshade (Solanum nigrum) and…”