Effects of testosterone propionate and polychlorinated biphenyls (PCB) on the activity of nonspecific esterases in the house mouse

Andersson, Margareta; Tegelström, Håkan

doi:10.1111/j.1601-5223.1979.tb01647.x

Cited by 8 publications

(1 citation statement)

References 18 publications

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“…Με την επίδραση της τεστοστερόνης αυξάνεται ο αριθμός των εστερασικών μορφών (εμφάνιση 3 επί πλέον που ονομάζονται Es-9) στα νεφρά ποντικού (von Deimling and Riebschlager, 1977). Η τεστοστερόνη επιπλέον επάγει τις εστεράσες του ορού και του συκωτιού στα θηλυκά άτομα των ποντικών και των νεφρών και στα δύο φύλα (Andersson and Tegel ström, 1979).…”

Section: μοριακή πολλαπλότητα των εστερασώνunclassified

Εστερασες Του Ψαριου Trachurus Trachurus. Κατανομη Καθαρισμος Και Φυσικοχημικος Χαρακτηρισμος Των Πολλαπλων Μοριακων Μορφων

Σαλαμαστρακησ¹

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Κατανομή και χαρακτηρισμός των πολλαπλών μοριακών μορφών των εστερασών του γένους Trachurus. 3.1.1. Ειδικότητα είδους των πολλαπλών εστερασικών μοριακών μορφών των λευκών μυών των ειδών του γένους Trachurus. 3.1.2. Κατανομή της εστερασικής ενεργότητας στους ιστούς του Τ. trachurus. 74 3.1.3. Επίδραση της ιοντικής ισχύος και του pH στην ενεργότητα των εστερασών εκχυλισμάτων συκωτιού, εντέρου και εγκεφάλου του Τ.trachurus. 3.1.4. Εκτίμηση του φαινομένου μοριακού βάρους της εστερασικής ενεργάτητας σε ιστούς του Τ. trachurus με μοριακή διήθηση. 3.1.5. Ισοηλεκτρικά σημεία των πολλαπλών εστερασικών μορφών ιστών του Τ. trachurus. 81 3.1.6. Ειδικότητα ιστού των πολλαπλών εστερασικών μοριακών μορφών του Τ. trachurus. 81 3.2. Καθαρισμός των πολλαπλών εστερασικών μορφών του συκωτιού του Τ. trachurus.

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Section: μοριακή πολλαπλότητα των εστερασώνunclassified

Εστερασες Του Ψαριου Trachurus Trachurus. Κατανομη Καθαρισμος Και Φυσικοχημικος Χαρακτηρισμος Των Πολλαπλων Μοριακων Μορφων

Σαλαμαστρακησ¹

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Pregnancy‐associated esterase in sera of baboons

1987

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Baboon serum samples were resolved by starch gel electrophoresis and polyacrylamide gradient gel electrophoresis and stained with naphthol substrates for esterase activity. An esterase that hydrolyzed alpha-naphthyl butyrate in preference to alpha-naphthyl acetate was found in very high activities in some individuals but not others. It migrated just cathodal of the albumin band in starch gels. In polyacrylamide gradient gels, it co-migrated with albumin and had an apparent molecular weight of approximately 65,000 daltons. Electrophoretic analysis by gel electrophoresis of random serum samples from male and female baboons indicated that this esterase was present only in the sera of pregnant baboons. Further investigation of serial samples collected from carefully monitored baboons confirmed that the amount of activity of this esterase was correlated with stage of pregnancy. Therefore, it was named pregnancy esterase (PE). PE was detectable by gel electrophoresis and chromogenic staining techniques as early as day 30 of pregnancy; its activity gradually increased with progressive pregnancy and reached maximum activity near full term (182 days). Soon after parturition, the activity of PE decreased rapidly and was not detected in maternal sera by day 14 postpartum. No evidence of PE was detected in sera of pregnant humans.

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Esterase-29 (ES-29): Biochemical characterization and control by two independent gene loci of a testosterone-dependent mouse serum esterase

Deimling

Gaa

1992

Biochem Genet

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Biochemistry and genetics of a testosterone-dependent murine serum esterase designated esterase-29 (ES-29) are described. The enzyme was identified after disc electrophoresis and subsequent staining for esterase using alpha-naphthyl acetate as the substrate. It was inhibited by bis-p-nitrophenyl phosphate and was resistant to p-chlorophenylsulphonate and hence was classified as carboxylesterase EC3.1.1.1. The molecular mass was estimated to be about 130 kDa. It was shown that ES-29 is under the control of two independent genes. The first, termed Es-29, is suggested to be a structural locus, linked to the cluster-2 esterase loci on chromosome 8. Three alleles at Es-29, Es-29a, Es-29b, and Es-29c are distinguished, which determine absence (SEG/1), strong activity (BALB/cJ), and low activity (MOLH/Fre), respectively. The second locus, termed Mse-1 (serum esterase modifying factor), was found to be closely linked to Pre-2 on chromosome 12 and is suggested to be a modifying or regulatory gene. Two alleles were distinguished, Mse-1a (BALB/cJ) and Mse-1m (MOL3/JA, Cas-Bgr), which determine whether ES-29 appears as a single band or a double band, respectively. Mse-1m is dominant to Mse-1a.

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Effects of testosterone propionate and polychlorinated biphenyls (PCB) on the activity of nonspecific esterases in the house mouse

Cited by 8 publications

References 18 publications

Εστερασες Του Ψαριου Trachurus Trachurus. Κατανομη Καθαρισμος Και Φυσικοχημικος Χαρακτηρισμος Των Πολλαπλων Μοριακων Μορφων

Εστερασες Του Ψαριου Trachurus Trachurus. Κατανομη Καθαρισμος Και Φυσικοχημικος Χαρακτηρισμος Των Πολλαπλων Μοριακων Μορφων

Pregnancy‐associated esterase in sera of baboons

Esterase-29 (ES-29): Biochemical characterization and control by two independent gene loci of a testosterone-dependent mouse serum esterase

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