Effects of taurine administration on exercise-induced fatigue and recovery

Takahashi, Yumiko; Hatta, Hideo

doi:10.7600/jpfsm.6.33

Cited by 8 publications

(3 citation statements)

References 53 publications

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“…Because of the involvement of mitochondria in energy production, there has been much interest in taurine in sports medicine in humans with reference to exercise-induced fatigue and recovery, as has been reviewed previously (53). In addition, a strong case has been made that taurine is the main buffer in mitochondria (54) and that it moderates mitochondrial oxidant production (55).…”

Section: Conditional Vitaminsmentioning

confidence: 99%

Prolonging healthy aging: Longevity vitamins and proteins

Ames¹

2018

Proc. Natl. Acad. Sci. U.S.A.

188

133

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It is proposed that proteins/enzymes be classified into two classes according to their essentiality for immediate survival/reproduction and their function in long-term health: that is, survival proteins versus longevity proteins. As proposed by the triage theory, a modest deficiency of one of the nutrients/cofactors triggers a built-in rationing mechanism that favors the proteins needed for immediate survival and reproduction (survival proteins) while sacrificing those needed to protect against future damage (longevity proteins). Impairment of the function of longevity proteins results in an insidious acceleration of the risk of diseases associated with aging. I also propose that nutrients required for the function of longevity proteins constitute a class of vitamins that are here named “longevity vitamins.” I suggest that many such nutrients play a dual role for both survival and longevity. The evidence for classifying taurine as a conditional vitamin, and the following 10 compounds as putative longevity vitamins, is reviewed: the fungal antioxidant ergothioneine; the bacterial metabolites pyrroloquinoline quinone (PQQ) and queuine; and the plant antioxidant carotenoids lutein, zeaxanthin, lycopene, α- and β-carotene, β-cryptoxanthin, and the marine carotenoid astaxanthin. Because nutrient deficiencies are highly prevalent in the United States (and elsewhere), appropriate supplementation and/or an improved diet could reduce much of the consequent risk of chronic disease and premature aging.

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Section: Conditional Vitaminsmentioning

confidence: 99%

Prolonging healthy aging: Longevity vitamins and proteins

Ames¹

2018

Proc. Natl. Acad. Sci. U.S.A.

188

133

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“…Furthermore, the total running distance to exhaustion on the treadmill was shown to be reduced by more than 80% [ 102 ]. At the same time, whole-body TauT knockout mice were characterised by a significantly decreased Tau level in tissues with severe intolerance to exercise [ 103 ]. Furthermore, mitochondrial ROS generation was significantly increased in Tau-deficient hearts and ultrastructural abnormalities were found in the muscles of TauT KO mice [ 104 , 105 ].…”

Section: Biological Roles Of Taumentioning

confidence: 99%

Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models

2021

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Natural antioxidants have received tremendous attention over the last 3 decades. At the same time, the attitude to free radicals is slowly changing, and their signalling role in adaptation to stress has recently received a lot of attention. Among many different antioxidants in the body, taurine (Tau), a sulphur-containing non-proteinogenic β-amino acid, is shown to have a special place as an important natural modulator of the antioxidant defence networks. Indeed, Tau is synthesised in most mammals and birds, and the Tau requirement is met by both synthesis and food/feed supply. From the analysis of recent data, it could be concluded that the direct antioxidant effect of Tau due to scavenging free radicals is limited and could be expected only in a few mammalian/avian tissues (e.g., heart and eye) with comparatively high (>15–20 mM) Tau concentrations. The stabilising effects of Tau on mitochondria, a prime site of free radical formation, are characterised and deserve more attention. Tau deficiency has been shown to compromise the electron transport chain in mitochondria and significantly increase free radical production. It seems likely that by maintaining the optimal Tau status of mitochondria, it is possible to control free radical production. Tau’s antioxidant protective action is of great importance in various stress conditions in human life, and is related to commercial animal and poultry production. In various in vitro and in vivo toxicological models, Tau showed AO protective effects. The membrane-stabilizing effects, inhibiting effects on ROS-producing enzymes, as well as the indirect AO effects of Tau via redox balance maintenance associated with the modulation of various transcription factors (e.g., Nrf2 and NF-κB) and vitagenes could also contribute to its protective action in stress conditions, and thus deserve more attention.

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“…In muscle, it is required for normal contractile function and exercise performance, as evidenced by the reduction in exercise time during enforced treadmill-running or swimming tests of taurine depleted mice 4,5) . Conversely, taurine supplementation supports exercise performance and recovery [6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of taurine content on skeletal muscle of exercised rats using MALDI-TOF MS imaging analysis

Komatsuzawa

Miyazaki

Ohmori

et al. 2020

JPFSM

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The amount of taurine and taurine derivatives in the body is affected by various diseases and physiological events, such as exercise. However, there is little information about possible changes in taurine distribution within tissue. In the present study, we examined whether matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS) can be used to determine the effect of exercise on the distribution and content of taurine and acetyltaurine, a taurine derivative present in skeletal muscle. Using 9-aminoacridine to detect the amino acids in tissue samples, the content of taurine and acetyltaurine in homogenates of skeletal muscle was measured by MALDI-IMS. While the intrinsic levels of taurine in skeletal muscle tissue were adequate to be detected by MALDI-IMS, that of acetyltaurine was not observed. Following 120-min of treadmill running (20m/min), taurine content of soleus and plantaris muscles significantly declined. In the gastrocnemius muscle, taurine content is higher in slow-twitch fiber than fast-twitch fiber. However, the taurine content was not significantly changed by treadmill running in both fast-and slow-twitch fiber of the gastrocnemius muscle. In conclusion, MALDI-IMS using 9-aminoacridine as a matrix could detect the distribution of taurine in skeletal muscle before and after exercise.

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Effects of taurine administration on exercise-induced fatigue and recovery

Cited by 8 publications

References 53 publications

Prolonging healthy aging: Longevity vitamins and proteins

Prolonging healthy aging: Longevity vitamins and proteins

Taurine as a Natural Antioxidant: From Direct Antioxidant Effects to Protective Action in Various Toxicological Models

Evaluation of taurine content on skeletal muscle of exercised rats using MALDI-TOF MS imaging analysis

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