“…On the other hand, thicker catheters may cause irritation in small bladders, but are more resistant to damage due to biting and to occlusion, and also are less likely to twist, especially in cystometries with freely moving animals. PE‐10 is usually used in mice studies,10, 18 in rats PE‐10,19 PE‐50,20–24 PE‐60,25 PE‐90,26, 27 and PE‐100,28 have been used, and for guinea pigs, PE‐100 or thicker tubing is employed 15, 29. For cystometry in anesthetized animals, the catheter can be inserted either via the urethra or via the bladder, and in this case, it can be externalized suprapubically.…”