Effects of subthalamic nucleus stimulation on spontaneous sensorimotor MEG activity in a Parkinsonian patient

Reliable recording and analysis of MEG-based corticokinematic coherence in the presence of strong magnetic artifacts

“…by vagus nerve stimulator (Carrette et al, 2011;Kakisaka et al, 2013;Song et al, 2009;Tanaka et al, 2009), or even by implanted electrodes used for deep brain stimulation (Mäkelä et al, 2007). However, it is not yet known whether artifacts that are generated close to the area that needs to be mapped can also be suppressed by tSSS.…”

Rejecting deep brain stimulation artefacts from MEG data using ICA and mutual information

“…Other studies removed the DBS artefact successfully by using spatial filters (Mäkelä et al, 2007;Airaksinen et al, 2011Airaksinen et al, , 2012Airaksinen et al, , 2015Ramírez et al, 2011;Oswal et al, 2015). While all these approaches have helped to minimize the effect of the DBS artefact, there is still a demand for an artefact rejection approach which enables retrieving oscillatory activity in different frequency ranges.…”

Fine tuning the correlation limit of spatio-temporal signal space separation for magnetoencephalography

“…To address this problem, the spatiotemporal signal space separation (tSSS) method was developed (Taulu and Simola, 2006). The method has demonstrated the ability to suppress the artifacts associated, e.g., with deep brain stimulation in patients with Parkinson's disease (Mäkelä et al, 2007) and with median nerve stimulation (Medvedovsky et al, 2007).…”

“…By allowing smaller CL values, signals with poorer SNR will be removed. In previous studies (Taulu and Simola, 2006;Medvedovsky et al, 2007;Mäkelä et al, 2007), the CL was set to 0.98. The influence of different CL values on tSSS processed data has not been studied in detail.…”

“…Subsequently, tSSS will recognize the correlated waveform as disturbance and reject it. The above mechanisms constitute the principal artifact of the deep brain stimulation in MEG and tSSS has been shown to successfully suppress them (Mäkelä et al, 2007).…”