Arch Pediatr Adolesc Med
 1951
DOI: 10.1001/archpedi.1951.02040040021003
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Effects of Streptomycin Upon the Human Fetus

Alan Rubin1
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Cited by 9 publications

(3 citation statements)
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“…When a vaginal plug was observed, the mother was treated with streptomycin (Sigma-Aldrich, St. Louis, MO) in the drinking water (4 g/L); the bottles were changed twice per week. Streptomycin is known to cross the placental membrane 35 . On giving birth, the mother was continued on streptomycin in the water; the pups, when weaned, were continued on the same dose in their drinking water.…”
Section: Methodsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…When a vaginal plug was observed, the mother was treated with streptomycin (Sigma-Aldrich, St. Louis, MO) in the drinking water (4 g/L); the bottles were changed twice per week. Streptomycin is known to cross the placental membrane 35 . On giving birth, the mother was continued on streptomycin in the water; the pups, when weaned, were continued on the same dose in their drinking water.…”
Section: Methodsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Retardation of growth and pronounced nervous hyper excitability [73]. Tolbutamide Increased incidences of fetal anomalies [74].…”
Section: Streptomycinmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…12,130 –137 In the first 4 months of pregnancy, theoretical risk of ototoxicity and nephrotoxicity is a concern based on animal studies. 37,133,138 –144 Damage to the eighth cranial nerve has been documented following gestational use of streptomycin and kanamycin. 12,145 Ototoxicity can potentially occur following exposure to any aminioglycoside but has not been demonstrated following gentamicin administration in small human studies nor with the remaining agents within the class.…”
Section: Antibioticsmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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