Effects of strain rate, mixing ratio, and stress–strain definition on the mechanical behavior of the polydimethylsiloxane (PDMS) material as related to its biological applications

Khanafer, Khalil; Duprey, Ambroise; Schlicht, Marty; Berguer, Ramón

doi:10.1007/s10544-008-9256-6

Cited by 230 publications

(178 citation statements)

References 23 publications

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“…The relationship between stress and strain is different for different materials, and can be depicted by plotting stress against strain. The stress-strain curve that we obtained is comparable with existing work that reported on the stress-strain relationship of PDMS [12]. It is also important to note that the stress-strain curve is highly influenced by the PDMS material properties, hence resulting in a nonlinear curve.…”

Section: Resultssupporting

confidence: 86%

Stress-strain relationship of PDMS micropillar for force measurement application

Johari

Shyan

2017

EPJ Web Conf.

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Abstract. There is an increasing interest to use polydimethylsiloxane (PDMS) based materials as biotransducers for force measurements in the order of micro to nano Newton. The accuracy of these devices relies on appropriate material characterization of PDMS and modelling to convert the micropillar deformations into the corresponding forces. Previously, we have reported on fabricated PDMS micropillar that acts as a cylindrical cantilever and was experimentally used to measure the force of the nematode C. elegans. In this research, similar PDMS micropillars are designed and simulated using ANSYS software. The simulation involves investigating two main factors that is expected to affect the force measurement performance; pillar height and diameter. Results show that the deformation increases when pillar height is increased and the deformation is inversely proportional to the pillar diameter. The maximum deformation obtained is 713 um with pillar diameter of 20 um and pillar height of 100 um. Results of stress and strain show similar pattern, where their values decreases as pillar diameter and height is increased.The simulated results are also compared with the calculated displacement. The trend for both calculated and simulated values are similar with 13% average difference.

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Section: Resultssupporting

confidence: 86%

Stress-strain relationship of PDMS micropillar for force measurement application

Johari

Shyan

2017

EPJ Web Conf.

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“…The covalent bonding between the vinyl group of part A and the silicon hydride of part B can be formed during the mixing process. 27 To measure mechanical properties, PDMS specimens with three different mixing ratios (ratio of A:B ¼ 5:1, 10:1, and 15:1) were prepared with two different PDMS wall thicknesses (3 mm and 6 mm). Part A and part B were well mixed with the suggested ratios and the solution was poured into the prepared cast (4 cm Â 6 cm).…”

Section: A Pdms Sample Preparationmentioning

confidence: 99%

“…Consequently, there have been several studies made on the characterization of PDMS properties. 26,27 PDMS mechanical properties were also dependent on three factors: the thinner concentration, temperature, and strain rate. 28 The lower the concentration of cross-linking agent, the less solid the viscous polymer becomes.…”

Section: Introductionmentioning

confidence: 99%

Deformation properties between fluid and periodic circular obstacles in polydimethylsiloxane microchannels: Experimental and numerical investigations under various conditions

2013

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Understanding the mechanical properties of optically transparent polydimethylsiloxane (PDMS) microchannels was essential to the design of polymer-based microdevices. In this experiment, PDMS microchannels were filled with a 100 lM solution of rhodamine 6G dye at very low Reynolds numbers ($10 À3 ). The deformation of PDMS microchannels created by pressure-driven flow was investigated by fluorescence microscopy and quantified the deformation by the linear relationship between dye layer thickness and intensity. A line scan across the channel determined the microchannel deformation at several channel positions. Scaling analysis widely used to justify PDMS bulging approximation was allowed when the applied flow rate was as high as 2.0 ll/min. The three physical parameters (i.e., flow rate, PDMS wall thickness, and mixing ratio) and the design parameter (i.e., channel aspect ratio ¼ channel height/channel width) were considered as critical parameters and provided the different features of pressure distributions within polymer-based microchannel devices. The investigations of the four parameters performed on flexible materials were carried out by comparison of experiment and finite element method (FEM) results. The measured Young's modulus from PDMS tensile test specimens at various circumstances provided reliable results for the finite element method. A thin channel wall, less cross-linker, high flow rate, and low aspect ratio microchannel were inclined to have a significant PDMS bulging. Among them, various mixing ratios related to material property and aspect ratios were one of the significant factors to determine PDMS bulging properties. The measured deformations were larger than the numerical simulation but were within corresponding values predicted by the finite element method in most cases. V C 2013 AIP Publishing LLC. [http://dx

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“…A two-dimensional computational model with H M = 25 µm was constructed for the valve "center" cross-section as indicated in the inset of Figure 1a. Because of the large deformation during the valve operation, we adopted the Neo-Hookean hyperelastic model [42] (Lamé constant µ = 678.6 kPa; Lamé constant λ = 1.0714 MPa) with the density ρ = 920 kg/m 3 , the Young's modulus E = 2.2 MPa [43], and the Poisson's ratio γ = 0.4 [44], in order to describe the mechanical behaviors of PDMS. For the material domains, triangular meshes were generated with an average element size of ~0.2 µm 2 ; and all peripheries of the flow channel region were set as contact pairs.…”

Section: Membrane Deformation Simulationmentioning

confidence: 99%

Dynamics of Microvalve Operations in Integrated Microfluidics

Lau

Yip

et al. 2014

Micromachines

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Pneumatic microvalves are widely used key components for automating liquid manipulation and flow control in microfluidics for more than one decade. Due to their robust operations and the ease of fabrication, tremendous microfluidic systems have been developed with the multiple microvalves for higher throughput and extended functionalities. Therefore, operation performance of the microvalves in the integrated microfluidic devices is crucial to the related applications, in fields such as micro-flows, cell analyses, drug discovery, and physical/chemical detections. It has been reported that operation performance of the microvalves are highly sensitive to the device configuration and pressurization scheme. This implies the further development of integrated microfluidics with a larger number of the valves may suffer the problems of undetermined microvalve behaviors during operations, which can become an unavoidable hurdle in the device design and optimization processes. Herein, we characterize responses of the individual microvalves for different operation configurations, e.g., membrane thicknesses and driving pressures. We investigate also the effects in microfluidics integrated with the more valves, through experiments, modeling and simulations. We show that dynamics of the microvalves is indeed influenced by the configurations, levels of design complexity and positions in the devices. Overall, taken dynamics of the microvalve responses into considerations, this work provides insights and guidelines for better designs of integrated microfluidics for the future applications requiring higher throughput and improved operation performance. OPEN ACCESSMicromachines 2014, 5 51

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Effects of strain rate, mixing ratio, and stress–strain definition on the mechanical behavior of the polydimethylsiloxane (PDMS) material as related to its biological applications

Cited by 230 publications

References 23 publications

Stress-strain relationship of PDMS micropillar for force measurement application

Stress-strain relationship of PDMS micropillar for force measurement application

Deformation properties between fluid and periodic circular obstacles in polydimethylsiloxane microchannels: Experimental and numerical investigations under various conditions

Dynamics of Microvalve Operations in Integrated Microfluidics

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