We conducted a prospective study on 10 excised larynges from patients affected by advanced\ud
laryngeal cancer, to assess the thermal-effect due to surgical incisions made at standard distance by\ud
using: scalpel, CO2 Laser, harmonic scalpel and electrocautery. Upon histopathological examination, thermal\ud
damage (Surgical Artifact, SA), tissue lost/retraction (Shrinkage, S), and tissue alterations were compared\ud
for each instrument