Effects of spinal cord lesions on cutaneously elicited reflexes in the decerebrate cat. Tonic bulbospinal and spinobulbar inhibitory systems

Dougherty, Margaret; Shea, Steven A.; Liu, C.N.; Chambers, W. W.

doi:10.1016/0014-4886(70)90149-4

Cited by 24 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A pathway carrying inhibitory information from the medullary reticular formation is located in the ventrolateral funiculus in the cat (Magoun & Rhines, 1946; Torvik & Brodal, 1957; Nyberg‐Hansen, 1965; Petras, 1967; Jankowska et al ., 1968), monkey (Kuypers et al ., 1962) and opossum (Beran & Martin, 1971; Martin & Dom, 1971), but in the dorsolateral funiculus of the cat (Holmqvist & Lundberg, 1959; Engberg et al ., 1968a,b; Dougherty et al ., 1970) and monkey (Chambers et al ., 1970). Further studies indicate that fibers arising from the RM cells descend in the dorsolateral funiculus (Brodal et al ., 1960; Dahlstrom & Fuxe, 1964).…”

Section: Discussionmentioning

confidence: 99%

Projections from the nucleus reticularis magnocellularis to the rat cervical cord using electrical stimulation and iontophoretic injection methods

et al. 2003

View full text Add to dashboard Cite

The aim of this study is to clarify the fiber distribution of the nucleus reticularis magnocellularis (NRMC) and adjacent areas in the rat spinal cord. Biotinylated dextran amine was injected iontophoretically through a glass capillary into the areas, in which a single cell responded to noxious electrical stimulation of the sciatic nerve and to a pinch of the thigh skin with multiple spikes. Labeled fibers descended bilaterally through the ventral funiculi of the medulla oblongata and then through the ventral and lateral funiculi of the cervical cord with an ipsilateral predominance, and terminated in the spinal gray (laminae I-X). A single fiber sometimes ran through several laminae while bifurcating many short branches with axon varicosities and terminal buttons in one transverse section, that is, through laminae V, VII and X, through laminae V, IIl-IV and I-II, and through laminae VII to I-II. The present study showed that the wide distribution of a single fiber and a mass of fibers descending from the NRMC and adjacent areas might modulate not only somatic sensory and motor functions but also autonomic functions in the spinal cord.

show abstract

Section: Discussionmentioning

confidence: 99%

Projections from the nucleus reticularis magnocellularis to the rat cervical cord using electrical stimulation and iontophoretic injection methods

et al. 2003

View full text Add to dashboard Cite

show abstract

“…In the decerebrate cat spinal transection induces an immediate release of cutaneous reflexes [8,31,40]. In the monkey, the reflex picture is overwhelmed by spinal shock [5].…”

Section: The Decerebrate Preparationmentioning

confidence: 99%

Anatomical and Physiological Correlates of Plasticity in the Central Nervous System

Chambers

Liu

McCouch³

1973

Brain Behav Evol

Self Cite

View full text Add to dashboard Cite

show abstract

Three bulbospinal pathways from the rostral medulla of the cat: An autoradiographic study of pain modulating systems

Basbaum¹,

Clanton²,

Fields³

1978

J of Comparative Neurology

610

View full text Add to dashboard Cite

Small amounts of 3H‐leucine were injected into discrete regions in the rostral medulla of the cat. Descending projections from these sites were studied with autoradiographic methods. On the basis of differential projections to the medulla and spinal cord, three distinct regions were delineated. Nucleus reticularis gigantocellularis (Rgc), located dorsally in the medullary reticular formation, projects primarily to “motor” related sites, including cranial motor nuclei VI, VII, XII, nucleus intercalatus, and a part of the ipsilateral medial accessory olive. The projection to the spinal cord is primarily via the ipsilateral ventrolateral and contralateral ventral funiculi. The Rgc terminal field is in lamina VII and VIII ipsilateral and lamina VIII contralateral to the injection site. In contrast, nucleus raphe magnus, (NRM) located ventrally, in the midline of the rostral medulla projects primarily to structures with known nociceptive and/or visceral afferent input. These sites include the solitary nucleus, the dorsal motor nucleus (X) and the marginal and gelatinous layers of the spinal trigeminal nucleus caudalis. The projection to the spinal cord is bilateral, via the dorsolateral funiculus. Terminal fields are found in the marginal zone and the substantia gelatinosa of the dorsal horn, and more deeply in lamina V, medial VI and VII. Nucleus reticularis magnocellularis (Rmc), located lateral to NRM and ventral to Rgc, has an overlapping projection with NRM, but the projection is ipsilateral. This difference between Rmc and Rgc is correlated with cytoarchitectural features of the two regions. The possibility that the raphe‐spinal pathway in the DLF mediates opiate and brain stimulation‐produced analgesia is discussed.

show abstract

Effects of spinal cord lesions on cutaneously elicited reflexes in the decerebrate cat. Tonic bulbospinal and spinobulbar inhibitory systems

Cited by 24 publications

References 12 publications

Projections from the nucleus reticularis magnocellularis to the rat cervical cord using electrical stimulation and iontophoretic injection methods

Projections from the nucleus reticularis magnocellularis to the rat cervical cord using electrical stimulation and iontophoretic injection methods

Anatomical and Physiological Correlates of Plasticity in the Central Nervous System

Three bulbospinal pathways from the rostral medulla of the cat: An autoradiographic study of pain modulating systems

Contact Info

Product

Resources

About