Effects of soybean pectin on blood glucose and insulin responses in healthy men

Abstract

Pectin is a soluble fiber with demonstrated health benefits such as the ability to lower blood glucose and cholesterol, increased satiety leading to lower caloric intake and improved insulin resistance. These benefits suggest that pectin may help in prevention and treatment of diseases such as diabetes and obesity. Soybean seed coats, a co‐product of soybean processing, are good source of fiber (pectin) and shows potential as a value‐added product. The objective of this study is to examine the effects of soy pectin on blood glucose and insulin responses. Using a randomized‐crossover design, fifteen healthy men were randomly assigned to two groups (control and soy pectin). Fasting finger‐stick blood samples were collected at 15 minutes before and 0, 15, 30, 45, 60, 75, 90, 120, and 180 minutes after consumption of control solution with added soy pectin or a control solution. Although no specific time interval was significantly different, a reduction in plasma glucose and insulin concentrations was observed. Compared with the control, mean glucose iAUC (incremental area under the curve) for the soy pectin treatment was lowered by ~13.2% from 5059 + 506 to 4390 + 387 µU (~3 h) L‐1. Results suggest soy pectin has a potential for use as a functional food ingredient to improve human health. Funding provided by Arkansas Soybean Promotion Board is greatly appreciated.

Evaluation of Hypoglycemic and Antioxidant Activities of Soybean Meal Products Fermented by Lactobacillus plantarum FPS 2520 and Bacillus subtilis N1 in Rats Fed with High-Fat Diet

“…Except for isoflavones, the hypoglycemic activity of other bioactive soybean components, such as protein, peptide, dietary fiber, pectin, and pinitol, has been reported [ 35 , 36 , 37 ]. In addition, bacteria per se, employed for fermentation, may also contribute to the bioactivities of fermented SBM.…”

Current Advancements in Pectin: Extraction, Properties and Multifunctional Applications

“…Pectin has shown beneficial effects in the prevention and treatment of lifestyle diseases such as diabetes and obesity. Soybean seed coats left as a by-product from soybean processing are a good source of pectin and fiber [ 168 ]. Two groups of fifteen healthy men were administered control and soy pectin, and blood samples were collected 15 min before feeding and after consumption of control solution with added soy pectin or the control solution, at intervals of 0, 15, 30, 45, 60, 75, 90, 120, and 180 min.…”

Pharmaceutical and drug delivery applications of pectin and its modified nanocomposites

“… Pectin and its nanocomposites Types of microbes Microbial strains Reference Pectin-oleate, pectin-linoleate, and pectin palmitate Bacteria S. aureus and E. coli [ 17 ] Ag NPs using pectin as the reducing and capping Pectin-based zirconium (IV) silicophosphate NCs Pectin–CdS NCs E. coli pectin Bacteria H. pylori [ 48 ] Pectin-Amphotericin B imine and amine conjugates Fungus C. albicans and A. fumigatus [ 49 ] Pectin Fungus Colletotrichum gloeosporioides, Fusarium oxysporum, Sclerotinia sclerotiorum and Mucor sp. [ 50 ] Pectin Fungus C. albicans and S. cerevisiae [ 51 ] Pectin Virus Herpesvirus type 1 (HSV -1) poliovirus strain (PV). [ 52 ] Pectin methylesterase Virus Tobacco Mosaic Virus [ 53 ] Pectin Virus Hepatitis B Virus Pectin Virus Herpes Simplex Virus Type 2 Pectin Virus SARS-CoV-2 …”

“… [ 82 ] High-methoxyl Homogalacturonan Hippophae rhamnoide ⁃ Increasing the production of lymphocytes, raising macrophage activity, and encouraging NK and CTL activity. [ 83 ] Pectin Portulaca oleracea L. C Antiviral Anti-HSV-2 activity [ 51 ] Pectin Saussurea laniceps Prevents ​the ​Hepatitis ​B ​virus ​from ​secreting ​its ​surface ​and ​envelope ​antigens ​in ​HepG2 ​cells. [ 84 ] Pectin Inga spp⁃ Prevent viral replication through binds to the glycoprotein and carboxyl groups on the cell membrane.…”