Effects of Some Analgesic Drugs Used in Childbirth. With Special Reference to Variation in Respiratory Minute Volume of the Newborn

Parenteral opioids for maternal pain management in labour

“…A further two studies did not focus on pain relief but rather on newborn serum bilirubin (McDonald 1964) or platelet function (Greer 1988). Seven studies focused on drugs no longer in use, or drugs not used nowadays for obstetric analgesia (Cahal 1960; Cavanagh 1966; Eames 1964; Ransom 1966; Roberts 1957; Sentnor 1966; Walker 1992). In five studies the same opioid was given to women in both arms of trials and the difference between groups was mode of administration; different modes of administration of parenteral opioids will be considered in a separate Cochrane review (Balki 2007; Isenor 1993; McInnes 2004; Rayburn 1989; Rayburn 1991).…”

“…Seven studies focused on drugs no longer in use, or drugs not used nowadays for obstetric analgesia (Cahal 1960; Cavanagh 1966; Eames 1964; Ransom 1966; Roberts 1957; Sentnor 1966; Walker 1992).…”

“…Studies that examine variation in mode of administration will be considered in a separate related Cochrane review Rayburn 1991 In this study both groups received the same drug (fentanyl) 1 group by PCA and 1 nurse administered (IV). Studies that examine variation in mode of administration will be considered in a separate related Cochrane review Roberts 1957 In this study a mood enhancing drug (methylpentonol) was compared with an analgesic (pethidine). The outcome was not pain relief but fetal expiratory volume.…”