Effects of Smoking on Plasma Testosterone Level and Erectile Function in Rats

Drug Addiction and Sexual Dysfunction

“…18 In addition, it was shown that nicotine can negatively affect the levels of sex hormones, testosterone and estrogen, in male and female smokers. 15,19 However, other studies did not report similar findings. 20,21 Clinical studies examining the effects of smoking on male erectile function reported its negative impact on the ability of a man to initiate or maintain an erection.…”

“…[13][14][15][16][17] The impact of smoking on erectile function, although more evident in older men, can be found in men under the age of 45 years. [14][15][16] There are several reasons smoking affects sexual function. 6,13 First, nicotine is considered a strong vasoconstrictor and therefore can significantly reduce blood flow to the male and female genitals during sexual activity.…”

Male Sexual Function and Smoking

“…Because animals cannot be made to smoke actively, the animals were passively exposed to smoke in a cage. 9,17,42,44,51,65 CONCLUSIONS There is substantial evidence showing that cigarette smoking contributes to ED. This association is supported by case series, cross-sectional, and prospective population-based studies.…”

Lifestyles and sexuality in men and women: the gender perspective in sexual medicine

“…It is important to emphasize that one of the effects of nicotine is to have a negative impact on sex hormones (androgens and estrogens) [64], and on clitoral blood flow [65]. Therefore, sexual symptoms such as hypo lubrication can be determined by the reduced flow of genital blood.…”

“…Therefore, sexual symptoms such as hypo lubrication can be determined by the reduced flow of genital blood. This condition can also lead to a delay in orgasm and a more general decline in sexual relationships and a sense of dissatisfaction for sexual intercourse and couple relationship [10,64,65].…”