2021
DOI: 10.1001/jamapsychiatry.2021.0326
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Effects of SlowMo, a Blended Digital Therapy Targeting Reasoning, on Paranoia Among People With Psychosis

Abstract: Key Points Question Can a brief blended digital therapy targeting reasoning (SlowMo) improve paranoia for adults with psychosis when added to usual care? Findings This randomized clinical trial of 361 individuals with clinical paranoia did not demonstrate that SlowMo therapy reduced the primary outcome of self-reported paranoia at 24 weeks compared with usual care only, although secondary beneficial effects were found on this measure at 12 weeks. Self-repor… Show more

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Cited by 55 publications
(61 citation statements)
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“…Both of these reasoning biases were involved in causal pathways that increased paranoia and the perceived dangerousness of vaccines, thereby reducing vaccine intentions and encouraging conspiracist ideation. Given this potential pathway, future research should investigate whether existing intervention that target these biases and/or paranoia, such as SlowMo and Metacognitive Training [19] , [35] , might be adapted to encourage vaccination and reduce conspiracist ideation. The possibility that these interventions might have these effects is particularly exciting given that existing interventions on vaccine intentions are frequently ineffective [42] or backfire [40] .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Both of these reasoning biases were involved in causal pathways that increased paranoia and the perceived dangerousness of vaccines, thereby reducing vaccine intentions and encouraging conspiracist ideation. Given this potential pathway, future research should investigate whether existing intervention that target these biases and/or paranoia, such as SlowMo and Metacognitive Training [19] , [35] , might be adapted to encourage vaccination and reduce conspiracist ideation. The possibility that these interventions might have these effects is particularly exciting given that existing interventions on vaccine intentions are frequently ineffective [42] or backfire [40] .…”
Section: Discussionmentioning
confidence: 99%
“…Determining whether the aforementioned factors indirectly impact vaccine intentions could support more effective intervention on vaccine uptake. Many of these factors (e.g., paranoia, reasoning biases) are modifiable [19] ; Steffen [35] and are therefore potential novel targets for interventions aiming to increase vaccine uptake. Novel interventions that encourage vaccination would be invaluable because commonly-used strategies are frequently ineffective [42] or backfire.…”
Section: Introductionmentioning
confidence: 99%
“…For example, the Actissist app targets negative symptoms (e.g., reduced socialization), general psychotic symptoms, mood, and cannabis misuse through offering tools to help with cognitive appraisals, belief conviction, emotions and associated behaviors 153 . Another app ( SlowMo ) targets paranoia through offering tools to help with jumping to conclusions and belief inflexibility as part of blended care 154 . A study of 361 patients with a diagnosis of schizophrenia, randomized to receive either SlowMo therapy or usual care, found no significant difference between groups on the primary outcomes related to paranoia at 24 weeks (the primary end‐point), though significant effects between groups were apparent post‐treatment 154 .…”
Section: Evidence For Digital Psychiatry Within Specific Contextsmentioning
confidence: 99%
“…Another app ( SlowMo ) targets paranoia through offering tools to help with jumping to conclusions and belief inflexibility as part of blended care 154 . A study of 361 patients with a diagnosis of schizophrenia, randomized to receive either SlowMo therapy or usual care, found no significant difference between groups on the primary outcomes related to paranoia at 24 weeks (the primary end‐point), though significant effects between groups were apparent post‐treatment 154 .…”
Section: Evidence For Digital Psychiatry Within Specific Contextsmentioning
confidence: 99%
“…Digital technologies also offer novel opportunities for individuals with paranoia: as a very broad generalisation, we might recognise that for some they might reduce anxieties about social engagements with clinicians, while equally appreciating that others might have concerns about the technology itself. Garety et al 2 tested ‘SloMo’, an eight-session digitally supported reasoning intervention, in 361 individuals with psychotic illness randomised to receive this or treatment as usual. The authors state that SloMo adopts an interventionalist-causal approach to enhancing CBT for psychosis by ‘targeting reasoning processes considered causal in psychosis’.…”
mentioning
confidence: 99%