Effects of sleep insufficiency on spatial working memory in low-pressure and hypoxic environments

Abstract

Background: This study aimed to investigate the effects of sleep insufficiency on spatial working memory in low-pressure and hypoxic environments. Methods: We selected 58 insufficient sleepers and 27 normal sleepers among the college students living in high-altitude areas for a long time to receive a spatial 2-back working memory task, while collecting behavioral and electroencephalograph data. We adopted an independent sample t-test and repeated measures analysis of variance to compare the differences in response time and accuracy, P2 and late positive potential components, and theta band energy values in the spatial working memory task between insufficient and normal sleepers. Results: We found no significant differences in response time and accuracy between the insufficient sleep group and the normal sleep group; however, the P2 peak value and the early theta band energy value were higher in the insufficient sleep group than in the normal sleep group. Conclusions: These results suggest that the spatial working memory ability of individuals with sleep insufficiency was weakened under low-pressure and low-oxygen environment.