Effects of Si/Zn Co‐Substitution on the Physicochemical Properties, In Vitro Angiogenic Potential, and Osteogenic Activity of β‐Tricalcium Phosphate
Yue He,
Teliang Lu,
Ziyang Xu
et al.
Abstract:Zinc ions have shown promising osteogenic activity, while silicon ions promote angiogenesis. In this study, we investigated the effects of silicon doping, zinc doping, and their co‐doping on the physicochemical properties, as well as the in vitro angiogenic and osteogenic activities of β‐tricalcium phosphate (β‐TCP). Our findings revealed that silicon doping primarily occurred on the P1 site, leading to lattice stability disruption in β‐TCP and favoring its transformation into α‐tricalcium phosphate (α‐TCP). N… Show more
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