Effects of Shock Waves on the Rat Ovary

McCullough, David L.; Yeaman, Leslie D.; Bo, Walter J.; Assimos, Dean G.; Kroovand, R. Lawrence; Griffin, Andrew; Furr, Elizabeth G.

doi:10.1016/s0022-5347(17)40928-1

Cited by 62 publications

(23 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The effects of shock waves on the reproductive systems have been reported in studies using chick embryos [1], rat ovaries [2], human spermatozoa [3] and rat testicles [4], No important effects on follicle number of fertility were noticed in the ovaries of female rats exposed to 1,500 shock waves at 15 keV. However in studies using chicken embryos, shock waves proved lethal to white leghorn chicken embryos ex ovo at all gestational ages.…”

Section: Discussionmentioning

confidence: 99%

“…While ESWL is apparently a safe and effective treatment, recent reports have shown that shock waves have a detrimental effect on normal cells. Various studies have examined the effects of disruption of the organogenesis of germ cells caused by the teratogenic potential of high energy shock waves in a number of sys tems, such as chick embryos [1], the ovarian function of rats [2], in vitro effects of human spermatozoa [3], and histomorphological changes in rat testicles [4], In order to clarify the effects of shock waves on the male reproductive system, this study investigates the motility and morpholo gy of human spermatozoa and morphological changes in rat testes following the application of shock waves. …”

mentioning

confidence: 99%

See 1 more Smart Citation

Effects of Shock Waves on the Male Reproductive System

et al. 1993

View full text Add to dashboard Cite

Although many reports concerning the effects of shock waves on the human body have been published, their effects on the male reproductive system are not well known. This report examines the effects of shock waves on human spermatozoa and rat testes. Semen samples were placed in water at 37 °C and 100, 200, 500, and 1,000 shock waves were applied. In proportion to an increasing number of shock waves, sperm motility and the percentage of viable sperm decreased, while the percentage of short-tailed sperm increased. In a second study 500 or 1,000 shock waves were applied to the testes of infant and adult male Wistar rats. Hematomas were observed macroscopically in the testes immediately after shock wave treatment. Light microscopy showed rupture of the basement membrane of the seminiferous tubules and outflow of spermatogenic cells. After 5 weeks, the treated testes appeared atrophic, with the absence of spermatogenic cells in the seminiferous tubules, except for Sertoli cells. Our data indicate that spermatozoa and the testis appear to be structurally damaged by shock waves.

show abstract

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Effects of Shock Waves on the Male Reproductive System

et al. 1993

View full text Add to dashboard Cite

show abstract

“…5,6 A study has also described the shortterm effects of shock waves on the rat ovary, indicating microscopic haemorrhages and some hypervascularity, but this apparently did not influence ovarian function or gestation. 7 Moran et al 8 described disastrous effects of shock waves on chick embryos; this study has served as the basis for the contraindication of ESWL during pregnancy.…”

Section: Introductionmentioning

confidence: 84%

The effect of extracorporeal shock wave lithotripsy on the rat spinal cord

et al. 2008

View full text Add to dashboard Cite

Study design: Experimental study. Objectives: To determine the effects of extracorporeal shock wave lithotripsy (ESWL) on the rat spinal cord. Methods: Animals were randomly divided into three groups. Groups 1 and 2 consisted of five rats each that underwent ESWL (2000 impulses at 15 kV and 2000 impulses at 18 kV, respectively) and group 3 contained five control rats (no shock wave treatment). ESWL-treated and control rats were compared with regard to light and electron microscopic findings of the adjacent spinal cord. Results: Gross neurological outcomes were normal in all groups. Light microscopic examination of group 1 showed extensive extravasation of red blood cells over all the interstitial spaces. Group 2 also had haemorrhagic areas and an irregular organization of axons in the white matter. Transmission electron microscopic examination of group 1 indicated extravasated red blood cells through the endothelium and swollen axoplasm, degenerated mitochondria, destruction of myelin sheaths and a slight increase in the number of lysosomes. Extravasated red blood cells were also seen in group 2. The axoplasmic mitochondria were enlarged, but no sign of mitochondrial degeneration was observed. Lamellar degeneration of myelin sheaths and abundant lysosomes were more predominant in group 2 than in group 1. Conclusion: Extracorporeal shock wave lithotripsy caused not only haemorrhage but also damage to neuronal structures except the nucleus. Our findings showed that higher-energy ESWL caused more myelin degeneration in the spinal cord.

show abstract

“…Thus the occurrence of vesicoureteral reflux or ureteral stricture that can accompany dilation of ureter to a nonreversible diameter was avoided [18][19][20]. The pulsed dye laser is transmitted through a thin and flexible quartz fiber and can be used through the channel of this ureteroscope [21,22]. However, the fine fiber often causes bleeding when it sticks to the ureteral wall where the stone is impacted and covered with edematous mucous membrane.…”

Section: Discussionmentioning

confidence: 99%

Transurethral Ureterolithotomy in 100 Lower Ureteral Stones

Hamano¹,

Tanaka²,

Suzuki³

et al. 1998

Urol Int

View full text Add to dashboard Cite

A total of 100 patients with lower ureter stones received transurethral ureterolithotripsy (TUL) using a pulsed dye laser and/or a pneumatic lithotriptor. Extracorporeal shock wave lithotripsy treatment was added in 15 patients because fragments larger than 4 mm had been pushed back to the renal pelvis. The median stone size was 8 mm (range 3–22 mm). Operative time ranged between 3 and 157 min with a median of 30 min. Stone size correlated well with impaction, when impaction was defined as the inability of a guidewire to pass over the stone. Complete removal was defined as total clearance at 1 month without retreatment. The overal stone-free rate was 93%. Among the 7 not-stone-free cases, 5 cases were considered to have been treated successfully because asymptomatic residual fragments were smaller than 4 mm, 1 case required retreatment to become stone free, and 1 case with a silent residual fragment of 8 mm had been followed up for 3 months. The success rate was 98% when successful treatment was defined as total clearance or the presence of asymptomatic residual fragments of 4 mm or less without retreatment. Impaction was not a significant determining factor of stone-free rate (95.7 and 86.7%, respectively, p >0.05) and in situ stone-free rate (TUL alone; 85.7 and 76.7%, respectively, p >0.05). Two minor ureteral perforations were encountered. No patient required percutaneous nephrostomy or open surgery, or showed any late complications. TUL is a safe and successful method in managing lower ureteral stones.

show abstract

Effects of Shock Waves on the Rat Ovary

Cited by 62 publications

References 8 publications

Effects of Shock Waves on the Male Reproductive System

Effects of Shock Waves on the Male Reproductive System

The effect of extracorporeal shock wave lithotripsy on the rat spinal cord

Transurethral Ureterolithotomy in 100 Lower Ureteral Stones

Contact Info

Product

Resources

About