Effects of severity of long-standing congestive heart failure on pulmonary function

Dimopoulou, Ioanna; Daganou, Maria; Tsintzas, Orestis K.; Tzelepis, George E.

doi:10.1016/s0954-6111(98)90136-6

Cited by 70 publications

(64 citation statements)

References 20 publications

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“…37 Another study has shown that as V · O2max falls, so does DLCO. 38 Siegel and colleagues found falls in DLCO correlated with reduced EF, but only in those patients found to have rales on clinical examination.…”

Section: Effects Of Hf On Respiratory Function Testingmentioning

confidence: 99%

Heart Failure and the Lung

Kee

Naughton

2010

Circ J

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Heart failure (HF) is a highly prevalent disease that leads to significant morbidity and mortality. There is increasing evidence that the symptoms of HF are exacerbated by its deleterious effects on lung function. HF appears to cause airway obstruction acutely and leads to impaired gas diffusing capacity and pulmonary hypertension in the longer term. It is postulated that this is the result of recurrent episodes of elevated pulmonary capillary pressure leading to pulmonary oedema and pulmonary capillary stress fracture, which produces lung fibrosis. It is likely that impaired lung function impairs the functional status of HF patients and makes them more prone to central sleep apnoea. (Circ J 2010; 74: 2507 - 2516

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Section: Effects Of Hf On Respiratory Function Testingmentioning

confidence: 99%

Heart Failure and the Lung

Kee

Naughton

2010

Circ J

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“…O padrão obstrutivo não é tão significativo em pacientes com marcada disfunção cardíaca, apesar de haver alguns relatos na literatura de também ser possível este padrão na ICC 6,25 .…”

Section: Discussionunclassified

“…Dimopoulou e colaboradores 25 Ainda neste ponto, Mortara e colaboradores 22 avaliaram a variável tempo de circulação pulmão-orelha que representa a análise simultânea do volume pulmonar instantâneo e SatO 2 registrados em um dado intervalo de tempo em segundos. Pacientes com respiração periódica e respiração de Cheyne-Stokes mostraram uma deficiência hemodinâmica mais pronunciada, com uma redução significativa do índice cardíaco (L/min/m 2 ) e um prolongamento do tempo de circulação pulmão-orelha (seg.)…”

Section: Discussionunclassified

Repercussões da cardiomegalia na função pulmonar de indivíduos adultos com insuficiência cardíaca crônica: uma revisão sistemática

Silva¹,

Lima²,

Reinaux³

et al. 2011

Fisioter. Pesqui.

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Para analisar as repercussões da cardiomegalia sobre a função pulmonar em indivíduos adultos com insuficiência cardíaca (IC) crônica, foram revisados artigos nas bases PUBMED, BIREME, ISI Web of Knowledge e COCHRANE, publicados na última década, estudos observacionais e sem restrição de idioma. Utilizados os descritores "cardiomegaly" e "Respiratory Function Tests", e negada a palavra "exercise". Foram incluídos artigos com IC crônica, de ambos os sexos, entre 19 e 64 anos, incluindo IC congestiva e cardiomiopatia dilatada e excluídos com IC aguda, com avaliações pós-intervenção clínica ou por exercício. Para avaliar a qualidade dos artigos foi utilizada a escala da Agency for Healthcare Research and Quality (AHRQ) e aceitos aqueles com escore>50 pontos (0-100). Foram selecionados cinco artigos do total de 1093 e agrupados por parâmetros relacionados aos fluxos e volumes pulmonares, padrão ventilatório e desempenho muscular. Na AHRQ, dois estudos ficaram na faixa de 50-75% e os demais >75%. Eles apontam para redução da capacidade vital inspiratória (CVI), volume expiratório forçado no 1º segundo (VEF1) e pressão inspiratória máxima (PImáx) em função da cardiomegalia, com discreta redução na relação VEF1/CVI e na capacidade de difusão para monóxido de carbono (DLCO). Portanto, segundo os estudos, a cardiomegalia leva a um padrão respiratório restritivo, com redução do volume alveolar que interfere na DLCO. As correlações mais fortes envolvem a redução da PImáx, CVI e VEF1.

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“…Moreover, it is common for patients with severe HF to have respiratory abnormalities of restrictive origin, airway obstruction and inspiratory muscle weakness, which further contributes to the dyspnoea experienced by these patients. Thus, it is relatively common to have restrictive as well as obstructive pulmonary abnormalities in the early course of HF [55].…”

Section: Epidemiologymentioning

confidence: 99%

Frequent non-cardiac comorbidities in patients with chronic heart failure

Dahlström

2005

European Journal of Heart Failure

104

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Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies used to treat them are discussed in the present paper.Hypertension is an important precursor of HF, and is still the most common risk factor for HF in the general population. About 50% of patients with untreated hypertension will develop HF. Pressure overload leads to the development of left ventricular hypertrophy (LVH) and diastolic dysfunction.Diabetes, which occurs in about 20-30% of patients with HF, is an important comorbidity resulting in morphological and metabolic disturbances affecting myocardial blood flow and hormonal regulation leading to a poor outcome and necessitating aggressive conventional treatment.Chronic obstructive pulmonary disease (COPD), occurs in approximately 20-30% of heart failure patients, and may complicate HF treatment, it is therefore important to recognize and treat it effectively.Finally, the early detection of anemia, which occurs in 20-30% of HF patients, is important since it is associated with functional impairment and increased mortality and morbidity. Combined treatment with erythropoietin and intravenous iron has shown beneficial effects on clinical symptoms and morbidity.In conclusion early detection of concomitant diseases in patients with HF is important and should be considered carefully when initiating therapy.

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Effects of severity of long-standing congestive heart failure on pulmonary function

Cited by 70 publications

References 20 publications

Heart Failure and the Lung

Heart Failure and the Lung

Repercussões da cardiomegalia na função pulmonar de indivíduos adultos com insuficiência cardíaca crônica: uma revisão sistemática

Frequent non-cardiac comorbidities in patients with chronic heart failure

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