Effects of secondary infections on the multidrug-resistant Tuberculosis: A cohort study

Tabriz, Nurlan; Nurtazina, Zhanara; Кожамуратов, М. Т.; Skak, Kuliya; Mutaikhan, Zhumat

doi:10.47176/mjiri.35.105

Cited by 5 publications

(2 citation statements)

References 18 publications

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“…A comparison of the complex morphological study of pleural fluid biopsies and the molecular analysis of GeneXpert MBT/Rif pleural biopsies for the purpose of confirming the diagnosis of tuberculosis with other similar scientific studies of the early detection of MBT in patients with pleurisy showed high diagnostic efficiency of the Xpert MBT/Rif analysis. This molecular genetic analysis is simple and quick to use, unlike most complex morphological systems [30,31]. This study made possible to fully analyze the efficiency of the GeneXpert method in detecting MBT in patients with unknown pleural effusion, using the information resource of our own sample of patients.…”

Section: N Resultsmentioning

confidence: 99%

Infezioni in Medicina

2023

Infez Med

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The purpose of the article was to explore the effectiveness of a complex morphological study of pleural biopsies and molecular genetic study (GeneXpert MBT/Rif) of pleural effusion in verifying the diagnosis of pleurisy of tuberculous aetiology. The participants of the study were 120 patients with a exudative pleurisy who were admitted to the department of extrapulmonary tuberculosis of the Regional Phthisiopulmonology Center (RPPC) in Aktobe (Republic of Kazakhstan) in the period from 2018 to 2020. Significant differences were obtained in the compared groups (p<0.05), which testifies to the rather high diagnostic efficiency of the GeneXpert MBT/RIF molecular genetic method in comparison with bacterioscopy in detecting Mycobacterium tuberculosis (MBT) in pleural fluid obtained by video thoracoscopy. Using the GeneXpert method, positive results of the presence of MBT in the pleural fluid were obtained in 26.3% of patients of the main group, while in patients of the control group, MBT was detected only in 3.2% of cases by simple bacterioscopy (p<0.05). The high diagnostic efficiency of the GeneXpert express method (26.3%) is confirmed and proven by the "gold standard" of bacteriological examination of pleural fluidthe growth of MBT colonies in 24.6% of cases by the BACTEC MGIT-960 method and in 28.1% of cases of MBT growth on solid nutrient medium Lowenstein-Jensen in patients of the main group. The combination of the invasive method of video thoracoscopy diagnostics with the GeneXpert microbiological express method for detecting MBT in the pleural fluid is today, the optimal method for early diagnosis of a drug-resistant form of exudative pleurisy of tuberculous etiology.

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Section: N Resultsmentioning

confidence: 99%

Infezioni in Medicina

2023

Infez Med

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“…The field of machine learning has enormous potential to solve complex problems in various industries, and using deep neural networks, especially RNNs, is a promising area. Due to their ability to analyse sequential data and learn complex patterns, machine learning technologies have transformed areas such as speech recognition, natural language processing and handwriting recognition (13)(14)(15)(16) , enabling businesses to achieve greater efficiency and productivity. One of the most important developments in the field of machine learning is the emergence of deep neural networks, especially RNNs.…”

Section: Introductionmentioning

confidence: 99%

Models of binary classification of the semantic colouring of texts

Boyko

2023

Innovaciencia

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Introduction: The purpose of the research is to compare different types of recurrent neural network architectures, namely the long short-term memory and gate recurrent node architecture and the convolutional neural network, and to explore their performance on the example of binary text classification. Material and Methods: To achieve this, the research evaluates the performance of these two popular deep-learning approaches on a dataset consisting of film reviews that are marked with both positive and adverse opinions. The real-world dataset was used to train neural network models using software implementations. Results and Discussion: The research focuses on the implementation of a recurrent neural network for the binary classification of a dataset and explores different types of architecture, approaches and hyperparameters to determine the best model to achieve optimal performance. The software implementation allowed evaluating of various quality metrics, which allowed comparing the performance of the proposed approaches. In addition, the research explores various hyperparameters such as learning rate, packet sizes, and regulation methods to determine their impact on model performance. Conclusion: In general, the research provides valuable insights into the performance of neural networks in binary text classification and highlights the importance of careful architecture selection and hyperparameter tuning to achieve optimal performance.

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Cardiopulmonary rehabilitation among patients with heart and chronic obstructive pulmonary disease in a hospital in Tirana

Necaj

2023

Med. perspekt.

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It is a well-known factor that the implementation of cardiopulmonary rehabilitation leads to a decrease in the number of deaths and morbidity, however, this method is not widely used in Albania. One of the possible factors of low demand is the ignorance of patients regarding the benefits and effectiveness of this method. The purpose of this study is to find out the level of awareness of patients with cardiopulmonary diseases. During the study, a cross-sectional survey method was used among patients with this disease. Interest in and use of this rehabilitation was assessed using questionnaires that were given to 690 patients who underwent a course of treatment in university clinics and research hospitals that provide cardiopulmonary resuscitation services. The results of the study show that a third of patients learned information about cardiopulmonary rehabilitation (CPR) from medical personnel, and the other part received it from doctors. Despite the fact that almost half of the patients knew that they should perform certain physical activities and exercises to maintain their positive dynamics in relation to cardiopulmonary disease, only one third of the patients understood that such everyday activities as climbing stairs and a brisk walk down the street do not constitute threats to their heart and lungs, respectively. It was also found that a significant part of the patients regularly played sports. Certain types of exercises were offered to one half of the patients, at that time, the rest of them performed various exercises. 69% of all patients who were given detailed information about CPR were ready to participate in this program. Despite the fact, that numerous people were ready to undergo this method of rehabilitation, not all of them were sufficiently knowledgeable and did not fully understand the essence of this technique. Also, an important factor in the positive dynamics of the patient's recovery is his relationship with the doctor and medical personnel involved in the treatment of patients with cardiopulmonary diseases.

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Effects of secondary infections on the multidrug-resistant Tuberculosis: A cohort study

Cited by 5 publications

References 18 publications

Infezioni in Medicina

Infezioni in Medicina

Models of binary classification of the semantic colouring of texts

Cardiopulmonary rehabilitation among patients with heart and chronic obstructive pulmonary disease in a hospital in Tirana

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