Effects of sea buckthorn (Hippophaë rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats

Xing, Jianfeng; Yang, Baoru; Dong, Yaling; Bing-Wen, Wang; Wang, Junxian; Kallio, Heikki

doi:10.1016/s0367-326x(02)00221-6

Cited by 145 publications

(79 citation statements)

References 4 publications

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“…In traditional medicine sea buckthorn has been used for treatment of stomach ulcers for its effect on anti-inflammatory mediators (Xing 2002). Oil and leaves support regeneration of skin wounds and support treatment of skin disorders (Upadhyay et al 2009).…”

Section: Anti-inflammatory Effectsmentioning

confidence: 99%

Sea buckthorn (Hippophae rhamnoides L.) as a potential source of nutraceutics and its therapeutic possibilities - a review

et al. 2015

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Sea buckthorn (Hippophae rhamnoides L.) is in the focus of interest mainly for its positive effects on health of both human and animal organisms. The whole plant of sea buckthorn and especially its berries are a source of a large number of different bioactive compounds. The greatest attention has been drawn to its high content of vitamins, minerals, natural antioxidants, n-3 and n-6 fatty acids, and proteins. Sea buckthorn is valued for its antioxidant, cardioprotective, antiatherogenic, antidiabetic, hepatoprotective, anti-carcinogenic, immunomodulatory, antiviral, antibacterial, anti-inflammatory and vasorelaxant effects. Due to these and other positive effects, the plant is included in both human and animal nutrition, in the latter case to increase the biological value of animal products. This review summarises the botanical characteristics of sea buckthorn, lists the bio-active substances contained in individual parts of the plant, their effects in the prevention of a number of different diseases and their possible utilisation in human and animal nutrition.

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Section: Anti-inflammatory Effectsmentioning

confidence: 99%

Sea buckthorn (Hippophae rhamnoides L.) as a potential source of nutraceutics and its therapeutic possibilities - a review

et al. 2015

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“…잘 익은 열매는 비타민 A, C, E와 K, carotenoids, 그리고 organic acids가 풍부하며 (Chen et al 1990;Yao and Tigerstedt 1992;Pintea et al 2001;Kallio et al 2002a), 강력한 항산화 (Eccleston et al 2002;Suleyman et al 2002), 궤양 유발 억제 (Suleyman et al 2001) 및 광 보호 효과 (Goel et al 2002)를 보인다. 펄프 오일과 종자 오일은 면역조절, 항산화 및 항미 생물 활성을 가지며 (Geetha et al 2002;Negi et al 2005), 위 궤양 (Suleyman et al 2001;Xing et al 2002), 피부 장애 (Yang et al 2000), 관상 동맥 질환 (Eccleston et al 2002), 방사선 노 출에 의한 산화적 피해 (Goel et al 2005 Isorhamnetin, kaempferol과 quereetin을 포함한 비타민나무 의 flavonoid는 다양한 약리효과 (항산화 , 세포독성 (Khatab et al 2006), 항암 (Fu et al 2004;Chen and Kang 2005;Niering et al 2005) 및 reverse multi-drug resistance activity (Chung et al 2005 (Fig. 4) …”

Section: 비타민나무의 약리 효과unclassified

Phamalogical effect and component of sea buckthorn(Hippophae rhamnoides L.)

김주성¹,

유창연²,

김명조³

2010

Journal of Plant Biotechnology

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Sea buckthorn (Hippophae rhamnoides L.) is deciduous shrubs in the genus Hippophae, mainly cultivated in Europe and Asia. Sea buckthorn berries have a high vitamin C, vitamin E, carotenoids, carbohydrates, protein, organic acids, dietary minerals, triterpenoids, polyphenolic acids and amino acids. Extracts of sea buckthorn berries have anti-obesity, anti-oxidantive, anti-microbial, anti-ulcerogenic, anti-diabetic and nutritional effects. Sea buckthorn used as a traditional medicine for the treatment of cough, aid digestion, invigorate blood circulation and alleviate pain. Extracts of sea buckthorn branches and leaves was administered to humans and animals to treat gastrointestinal distress in Mongolia. This paper briefly reviews the most relevant experimental data on the pharmacological effects and isolated component of sea buckthorn. And, we also describe the importance of sea buckthorn as the environmental-friendly crops.

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“…Hippophae rhamnoides L. (F. Elaeagnaceae), commonly known as seabuckthorn, has been exploited extensively in Indian and Tibetan traditional medicine for the treatment of circulatory disorders, ischemic heart disease, hepatic injury, and neoplasia [Xing et al, 2002;Gao et al, 2003;Guliyev et al, 2004]. H. rhamnoides also provides protection against radiation-induced lethality in mice and has free-radical scavenging activity .…”

Section: Introductionmentioning

confidence: 99%

Protection from radiation‐induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides

Shukla

Chaudhary

Kumar

et al. 2006

Environ and Mol Mutagen

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Hippophae rhamnoides or seabuckthorn is used extensively in Indian and Tibetan traditional medicine for the treatment of circulatory disorders, ischemic heart disease, hepatic injury, and neoplasia. In the present study, we have evaluated the radioprotective potential of REC-1001, a fraction isolated from the berries of H. rhamnoides. Chemical analysis of the extract indicated that REC-1001 was approximately 68% by weight polyphenols, and contained kaempferol, isorhamnetin, and quercetin. The effect of REC-1001 on modulating radiation-induced DNA damage was determined in murine thymocytes by measuring nonspecific nuclear DNA damage at the whole genome level using the alkaline halo assay and by measuring sequence/gene-specific DNA damage both in nuclear DNA (beta-globin gene) and in mitochondrial DNA using a quantitative polymerase chain reaction. Treatment with 10 Gy resulted in a significant amount of DNA damage in the halo assay and reductions in the amplification of both the beta-globin gene and mitochondrial DNA. REC-1001 dose-dependently reduced the amount of damage detected in each assay, with the maximum protective effects observed at the highest REC-1001 dose evaluated (250 micro g/ml). Studies measuring the nicking of naked plasmid DNA further established the radioprotective effect of REC-1001. To elucidate possible mechanisms of action, the antioxidant properties and the free-radical scavenging activities of REC-1001 were evaluated. REC-1001 dose-dependently scavenged radiation-induced hydroxyl radicals, chemically-generated superoxide anions, stabilized DPPH radicals, and reduced Fe(3+) to Fe(2+). The results of the study indicate that the REC-1001 extract of H. rhamnoides protects mitochondrial and genomic DNA from radiation-induced damage. The polyphenols/flavonoids present in the extract might be responsible for the free radical scavenging and DNA protection afforded by REC-1001.

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Effects of sea buckthorn (Hippophaë rhamnoides L.) seed and pulp oils on experimental models of gastric ulcer in rats

Cited by 145 publications

References 4 publications

Sea buckthorn (Hippophae rhamnoides L.) as a potential source of nutraceutics and its therapeutic possibilities - a review

Sea buckthorn (Hippophae rhamnoides L.) as a potential source of nutraceutics and its therapeutic possibilities - a review

Phamalogical effect and component of sea buckthorn(Hippophae rhamnoides L.)

Protection from radiation‐induced mitochondrial and genomic DNA damage by an extract of Hippophae rhamnoides

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