Effects of<scp>L</scp>-Arginine,<scp>L</scp>-NAME, Methylene Blue, and Their Combinations on<i>Corchorus olitorius</i>. Aqueous Extract Antinociception in Mice

Zakaria, Zaki Yamani; Somchit, M. N.; ., M.R. Sulaiman; Jais, Abdul Manan Mat; ., C.A. Fatimah

doi:10.1080/13880200600798478

Cited by 3 publications

(1 citation statement)

References 36 publications

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“…Channa striatus, is a highly priced air-breathing freshwater fish and are in great demand as food fish due to their appealing flavour [1], few muscular spines, medicinal importance [2][3][4][5][6] and air-breathing nature [4] that facilitate high density culture and easy transport in live condition to the markets. Murrel adapts well to hypoxic water-bodies and hence can be cultured in high stocking densities.…”

Section: Introductionmentioning

confidence: 99%

Effect of various dietary fats supplementation on the liver glycogen, protein and digestive enzymes activities in striped murrel, Channa striatus

Dayal¹,

Srivastava²,

Jena³

et al. 2016

J App Biol Biotech

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A 84-days experiment was conducted to observe the effects of different feeds rich with various types of fats on selected biochemical parameters of Channa striatus grow-outs. There were seven treatments (F1, L3HUF; F2, H3HUF; F3, MUSOL; F4, LINOL; F5, MIXOL; F6, SATOL and F7, NATFO), fed to fish (avg. wt., 27.36 ± 0.09 to 32.54 ± 0.41 g). Results showed that the variation in liver glycogen content was recorded on ad dition of different fat content in the diet. Activity of intestine protease recorded significantly (p<0.05) on addition of various fat content in the diet. It is found that the variation in intestine amylase varied significantly (p<0.05) in F1, F3 and F5 feeding trials. Intestine lipase varied significantly on addition of various fat content in all the feeding trials except in NATFO. The intestine cellulase was very poor in this fish and does not varied significantly (p > 0.5) on addition of different fat content in the diet. In case of F1 and F2 there was no activity recorded till end. Results suggests that dietary fat has direct role in the alteration of biochemical parameters especially intestinal lipase which showed drastic variation in the activity in this species of aquaculture importance.

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Section: Introductionmentioning

confidence: 99%

Effect of various dietary fats supplementation on the liver glycogen, protein and digestive enzymes activities in striped murrel, Channa striatus

Dayal¹,

Srivastava²,

Jena³

et al. 2016

J App Biol Biotech

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Channa Striatus Protects Against PTZ-Induced Seizures in LPS Pre-conditioned Zebrafish Model

et al. 2022

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Epilepsy is a neurological disorder characterized by recurrent unprovoked seizures. Mounting evidence suggests the link between epileptogenesis and neuroinflammation. We hypothesize that eliminating neuroinflammation can alleviate seizure severity and prolong seizure onset. Channa striatus (CS) is a snakehead murrel commonly consumed by locals in Malaysia, believed to promote wound healing and mitigate inflammation. This study aims to unravel the anticonvulsive potential of CS extract on neuroinflammation-induced seizures using an adult zebrafish model. Neuroinflammation was induced via cerebroventricular microinjection of lipopolysaccharides from E. coli and later challenged with a second-hit pentylenetetrazol at a subconvulsive dose of 80 mg/kg. Zebrafish behaviour and swimming pattern analysis, as well as gene expression analysis, were done to study the pharmacological property of CS. CS extract pre-treatment in all doses significantly reduced seizure score, prolonged seizure onset time and slightly improved the locomotor swimming pattern of the zebrafish. CS extract pre-treatment at all doses significantly reduced the expression of NFKB gene in the brain, and CS extract at 25 mg/L significantly reduced the IL-1 gene expression suggesting anti-neuroinflammatory properties. However, there were no significant changes in the TNFα. Besides, CS extract at 50 mg/L also elevated the expression of the CREB gene, which exerts neuroprotective effects on the neurons and the NPY gene, which plays a role in modulating the inhibition of the excitatory neurotransmission. To sum up, CS extract demonstrated some anticonvulsive and anti-inflammatory activity on neuroinflammation-induced seizures. Still, more studies need to be done to elucidate the mechanism of action of CS extract.

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In vivo effects of Channa striatus on humans and animals: a systematic review

hadi¹,

Ooi²,

Kadir³

et al. 2021

IFRJ

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Channa striatus contains biochemical components and albumin, which elicit beneficial effects to the consumers. This review aimed to clarify the effects of Channa striatus consumption on humans and animals in in vivo studies. A systematic search in four electronic databases namely ProQuest, EBSCOhost, PubMed, and SpringerLink was performed to choose the studies on Channa striatus as the interventions, and its effects on animals and humans. The intervention involved: (i) Channa striatus with placebo-controlled, (ii) Channa striatus pre-treated and treated with drugs, (iii) Channa striatus with the combination of Chronic Unpredictable Mild Stress (CUMS), and (iv) Channa striatus pre-treated with amino acids and methylene blue. Thirteen animal studies and seven human studies were included in the final analysis. They investigated the effects of Channa striatus on wound healing, anti-depressant-like effects, anti-inflammatory effects, and effects on human diseases. Consumption of Channa striatus supplements was found in seven studies to benefit wound healing processes due to the contents of amino acids and fatty acids found in Channa striatus extract. Two studies were found regarding Channa striatus lipid decreased the corticosterone level and nuclear factor-kappa B, while two studies reported of DHA content in Channa striatus inhibited the production of inflammatory mediators. Channa striatus elicits a positive effect on the wound healing process and enhanced antidepressant-like and anti-inflammatory effects due to its high content of amino acids and fatty acids.

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Effects ofL-Arginine,L-NAME, Methylene Blue, and Their Combinations onCorchorus olitorius. Aqueous Extract Antinociception in Mice

Cited by 3 publications

References 36 publications

Effect of various dietary fats supplementation on the liver glycogen, protein and digestive enzymes activities in striped murrel, Channa striatus

Effect of various dietary fats supplementation on the liver glycogen, protein and digestive enzymes activities in striped murrel, Channa striatus

Channa Striatus Protects Against PTZ-Induced Seizures in LPS Pre-conditioned Zebrafish Model

In vivo effects of Channa striatus on humans and animals: a systematic review

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