The chemical quality of ground water in the upper glacial (water-table) aquifer in Nassau and Suffolk Counties was examined in relation to 10 types of land use to evaluate the effect of human activities on ground water. The upper glacial aquifer, which consists of unconsolidated Pleistocene deposits composed primarily of sand and gravel, overlies thick Cretaceous deposits that form the bulk of the island's aquifer system. The aquifers are the sole source of drinking water for more than 2.6 million people in the two-county area. Contamination has restricted the use of the upper glacial aquifer for public-water supply in developed areas; thus, its use is restricted except in rural areas of Suffolk County. Median concentrations of total dissolved solids and detection frequencies of tetrachloroethylene, trichloroethylene, and 1,1,1-trichloroethane were higher in sewered areas than in unsewered areas. This indicates that the effects of sewering in the highly developed areas of Nassau and Suffolk Counties may be obscured by other factors, such as (1) concentration of commerce and industry in sewered areas, which are sources of leaks and spills of these contaminants, and (2) potential leakage from sewers. Also, some contaminants that were present in areas before sewer installation may persist within the aquifer system. Public Water Supply, provided lists of contaminated public-supply wells and analytical data on organic compounds in samples collected during local studies in Nassau County. James Mulligan and Richard Liebe of the Nassau County Department of Public Works, Water Supply Unit, provided analytical data on organic compounds in samples collected from the county's observation-well network. Arthur Kunz and Edith Tannenbaum of the Long Island Regional Planning Board, and Peter French of Resources Planning Associates, Inc., provided land-use data and help in data interpretation. Carole Swick and Roy Fedelem of the Long Island Regional Planning Board provided population-density statistics. Funding was provided by the U.S. Geological Survey's Toxic Waste-GroundWater Contamination Program.