Effects of Rowachol on prevention of postcholecystectomy pain after laparoscopic cholecystectomy: prospective multicenter randomized controlled trial

Abstract

Rowachol might be beneficial for prevention of PCP after laparoscopic cholecystectomy.

Long-term patient-reported outcomes following laparoscopic cholecystectomy

“…When LC is recommended, many patients wonder about the relief of their symptoms including pain and the occurrence of new symptoms after removing the GB. [ 29 , 30 ] As a result, PRO measurement has been useful as a significant determinant of patient satisfaction following cholecystectomy. [ 12 , 13 ] The GIQLI is 1 of the most widely used and validated questionnaires for the objective measurement of QoL including GB disease.…”

“…We previously reported that a score indicative of higher difficulty in performing LC, in the absence of other definite visceral organ damage, was an independent risk factor in developing short-term postoperative pain. [ 29 ] This may be because difficulty in dissection of the triangle formed by the common bile duct, cystic duct, and liver (Calot's triangle) may cause intraoperative nerve damage innervating the visceral structures. [ 8 , 29 ] Preoperative PTGBD has been widely used and has had the benefits of a low complication rate, being a simple operation with early symptom relief and improvements in cases of acute cholecystitis.…”

“…[ 29 ] This may be because difficulty in dissection of the triangle formed by the common bile duct, cystic duct, and liver (Calot's triangle) may cause intraoperative nerve damage innervating the visceral structures. [ 8 , 29 ] Preoperative PTGBD has been widely used and has had the benefits of a low complication rate, being a simple operation with early symptom relief and improvements in cases of acute cholecystitis. [ 38 , 39 ] Despite these positive effects on the management of patients, the effects of PTGBD on operative duration and open conversion rates reflecting surgical difficulties have not been identified clearly in patients with acute cholecystitis.…”

Protective efficacy of combined use of parecoxib and dexmedetomidine on postoperative hyperalgesia and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients

“…Laparoscopic cholecystectomy is widely accepted as the standard operation for benign gallbladder disease 1 , including gallstones 2 , acute or chronic cholecystitis 3 , 4 and biliary pancreatitis 5 . Despite the well-known advantages of laparoscopic cholecystectomy compared to open cholecystectomy, such as being a safer, more effective procedure, with less complications 6 , the postoperative pain and cognitive dysfunction (POCD) are still two major problems influencing patients' recovery 7 , 8 .…”

Postcholecystectomy syndrome: symptom clusters after laparoscopic cholecystectomy

“…Since its introduction in 1986, laparoscopic cholecystectomy (LC) has been more widely used and it is now considered the treatment of choice for various gallbladder (GB) diseases [ 1 2 3 4 5 6 ]. However, many patients remain symptomatic after cholecystectomy.…”