Effects of Resonant Electromagnetic Fields on Biofilm Formation in Pseudomonas aeruginosa

Abstract

The global rise of antimicrobial resistance (AMR) constitutes a future health threat and dictates a need to explore alternative and non-chemical approaches. The aim of this study was to explore the use of weak resonant electromagnetic fields as a method to disrupt biofilm formation of a pathogenic bacterium in cystic fibrosis patients. We developed a bioresonance laboratory setup able to distinguish between changes in planktonic growth and changes in biofilm formation and showed that certain resonant frequencies were able to affect biofilm formation without affecting planktonic growth. In addition, we show that the ambient day-to-day magnetic field affects biofilm formation in a non-consistent manner. Overall, we conclude that our assay is suitable for studying the potential of resonant magnetic fields as a treatment and prevention strategy to prevent biofilm infections, and that certain resonant frequencies may be used as future medical applications to combat antimicrobial resistance.

Magnetically Cured Macroradical Epoxy as Antimicrobial Coating

“…Consequently, recent research selected an analogous nitroxide radical undergoing an epoxy‐amine reaction as the ideal candidate for studying magnetic phenomena [27] . Interestingly, another study suggests that resonant magnetic fields may specifically interfere with microbial biofilm formation [28] . In the blending experiment mentioned above, the number of radicals was diluted with a non‐radical bearing monomer, minimizing the radical‐to‐radical interactions.…”

“…[27] Interestingly, another study suggests that resonant magnetic fields may specifically interfere with microbial biofilm formation. [28] In the blending experiment mentioned above, the number of radicals was diluted with a non-radical bearing monomer, minimizing the radical-to-radical interactions. However, inducing the radicals to orient in an ordered fashion by the external magnetic field in the blend enhanced radical-to-radical interactions, although these interactions are highly localized on the surface.…”

AC Electromagnetic Field Controls the Biofilms on the Glass Surface by Escherichia coli & Staphylococcus epidermidis Inhibition Effect

“…The inhibition The effects of electromagnetic fields have recently been examined from a variety of perspectives. For example, Haagensen et al [55] have obtained interesting results from experiments with smaller flux densities and lower frequency ranges. Cample et al [56] performed experiments at the same magnetic flux density around 1 mT as the authors, but in a lower frequency range.…”

A prospective study of patients with post treatment Lyme disease syndrome treated with modified VFEM energy

“…In the search for an affordable, dependable treatment for Lyme disease we are exploring the optimal therapeutic use of electromagnetic energy. A search of the literature yielded isolated in vitro research using magnetic fields for its direct antibacterial effects or potentiation of antibiotic therapy 1,3–12 . Earlier this year, we reported on five patients treated with high intensity electromagnetic energy for Post Treatment Lyme Disease Syndrome (PTLDS) or Chronic Lyme Disease (CLD) 13 .…”

“…A search of the literature yielded isolated in vitro research using magnetic fields for its direct antibacterial effects or potentiation of antibiotic therapy. 1,[3][4][5][6][7][8][9][10][11][12] Earlier this year, we reported on five patients treated with high intensity electromagnetic energy for Post Treatment Lyme Disease Syndrome (PTLDS) or Chronic Lyme Disease (CLD). 13 The number of treatments varied as well as the interval between treatments, ranging from days to months, due to patient location.…”