Effects of resistant starch on anti-obesity status and nutrient digestibility in dogs

Cho, Hyun-Woo; Seo, Kangmin; Chun, Ju Lan; Jeon, Jung-Hwan; Kim, Chan Ho; Lim, Seung-Taek; Cheon, Si Nae; Kim, Ki‐Hyun

doi:10.5187/jast.2023.e11

Cited by 4 publications

(3 citation statements)

References 41 publications

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“…Recent studies focusing on canines reveal alarming statistics, with 29%–34% of dogs classified as overweight and 5%–8% diagnosed as obese. These findings underscore the prevalence of pet obesity and its potential impact on the health and well-being of companion animals, mirroring the concerns associated with metabolic disorders in human health ( 3 – 5 ).…”

Section: Introductionmentioning

confidence: 64%

Dietary supplementation with probiotics promotes weight loss by reshaping the gut microbiome and energy metabolism in obese dogs

Kang,

Kwak,

Lee

et al. 2024

Microbiol Spectr

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Obesity and overweight among companion animals are significant concerns, paralleling the issues observed in human populations. Recent research has highlighted the potential benefits of various probiotics in addressing weight-related changes, obesity, and associated pathologies. In this study, we delved into the beneficial probiotic mechanisms in high-fat-induced obese canines, revealing that Enterococcus faecium IDCC 2102 (IDCC 2102) and Bifidobacterium lactis IDCC 4301 (IDCC 4301) have the capacity to mitigate the increase in body weight and lipid accumulation in obese canines subjected to a high-fat diet and hyperlipidemic Caenorhabditis elegans ( C. elegans ) strain VS29. Both IDCC 2102 and IDCC 4301 demonstrated the ability to reduce systemic inflammation and hormonal disruptions induced by obesity. Notably, these probiotics induced modifications in the microbiota by promoting lactic acid bacteria, including Lactobacillaceae , Ruminococcaceae , and S24-7 , with concomitant activation of pyruvate metabolism. IDCC 4301, through the generation of bacterial short-chain fatty acids and carboxylic acids, facilitated glycolysis and contributed to ATP synthesis. Meanwhile, IDCC 2102 produced bacterial metabolites such as acetic acid and butyric acid, exhibiting a particular ability to stimulate dopamine synthesis in a canine model. This stimulation led to the restoration of eating behavior and improvements in glucose and insulin tolerance. In summary, we propose novel probiotics for the treatment of obese animals based on the modifications induced by IDCC 2102 and IDCC 4301. These probiotics enhanced systemic energy utilization in response to high caloric intake, thereby preventing lipid accumulation and restoring stability to the fecal microbiota. Consequently, this intervention resulted in a reduction in systemic inflammation caused by the high-fat diet. IMPORTANCE Probiotic supplementation affected commensal bacterial proliferation, and administering probiotics increased glycolysis and activated pyruvate metabolism in the body, which is related to propanate metabolism as a result of pyruvate metabolism activation boosting bacterial fatty acid production via dopamine and carboxylic acid specialized pathways, hence contributing to increased ATP synthesis and energy metabolism activity.

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Section: Introductionmentioning

confidence: 64%

Dietary supplementation with probiotics promotes weight loss by reshaping the gut microbiome and energy metabolism in obese dogs

Kang,

Kwak,

Lee

et al. 2024

Microbiol Spectr

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“…However, the majority of farmersapproximately 95%-in South Korea use non-circulating hydroponic systems with low facility costs [1,2,20,26]. This indicates an urgent requirement to establish agricultural recycling technologies to reduce the environmental pollution caused by the discharge of waste nutrients from non-circulating hydroponic systems [1,2,4,27].…”

Section: Introductionmentioning

confidence: 99%

Variation in Pathogenic Organisms as Affected by Using Hydroponic Nutrient Wastewater in Horticultural Facilities

et al. 2022

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Among the horticulture facilities in Korea, the hydroponic cultivation method has been increasingly used. This study aimed to identify fungi and bacterial species in hydroponic cultivation and highlight the need for sterilization to recycle the discharged drainage. Samples were collected from a number of paprika, tomato, and strawberry hydroponic greenhouses. Vinyl and glass greenhouses were studied, and the drainage discharge was of two types: direct discharge and collection after discharge. In total, 24 fungal and six bacterial species were detected from 399 and 151 densities, respectively. The primary fungal and bacterial species identified were from the genera Fusarium, Pythium, and Phytophthora as well as Agrobacterium and Pseudomonas. Statistical analysis revealed that the species number and density of fungi and bacteria were higher in strawberry than in tomato or paprika. These values were higher for vinyl greenhouses than for glass greenhouses. This study on the reuse of drainage from hydroponic greenhouses may contribute to the recycling of resources and reduction in water pollutant emission; this will thus help us to implement sustainable horticulture practices.

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“…Conversely, phage therapy alleviates concerns about antibiotic resistance, and according to the literature, phage resistance often lowers the pathogenicity of bacteria, significantly reducing the associated risks [106][107][108]. Consequently, while research in phage therapy for companion animals may be in its early stages, the growing societal recognition of pets as integral family members suggests that phage therapy holds potential as a research topic for treating various diseases in companion animals [109,110].…”

Section: Discussionmentioning

confidence: 99%

The current state of phage therapy in livestock and companion animals

Choi,

Lee,

Kwon

et al. 2024

J Anim Sci Technol

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In a global context, bacterial diseases caused by pathogenic bacteria have inflicted sustained damage on both humans and animals. Although antibiotics initially appeared to offer an easy treatment for most bacterial infections, the recent rise of multidrug-resistant bacteria, stemming from antibiotic misuse, has prompted regulatory measures to control antibiotic usage. Consequently, various alternatives to antibiotics are being explored, with a particular focus on bacteriophage (phage) therapy for treating bacterial diseases in animals. Animals are broadly categorized into livestock, closely associated with human dietary habits, and companion animals, which have attracted increasing attention. This study highlights phage therapy cases targeting prominent bacterial strains in various animals. In recent years, research on bacteriophages has gained considerable attention, suggesting a promising avenue for developing alternative substances to antibiotics, particularly crucial for addressing challenging bacterial diseases in the future.

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Effects of resistant starch on anti-obesity status and nutrient digestibility in dogs

Abstract: Effects of resistant starch on anti-obesity status and nutrient digestibility in dogs Running Title (within 10 words)Anti-obesity effect of corn-resistant starch in dogs

Cited by 4 publications

References 41 publications

Dietary supplementation with probiotics promotes weight loss by reshaping the gut microbiome and energy metabolism in obese dogs

Dietary supplementation with probiotics promotes weight loss by reshaping the gut microbiome and energy metabolism in obese dogs

Variation in Pathogenic Organisms as Affected by Using Hydroponic Nutrient Wastewater in Horticultural Facilities

The current state of phage therapy in livestock and companion animals

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