Effects of resistance training in combination with coenzyme Q10 supplementation in patients with post-polio: a pilot study

Skough, Katarina; Krossén, Charlott; Heiwe, Susanne; Theorell, H; Borg, Kristian

doi:10.2340/16501977-0245

Cited by 34 publications

(16 citation statements)

References 6 publications

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“…However, in a randomized trial of post‐polio patients, the combination of resistance training and coenzyme Q10 did not result in improvements in muscle strength, endurance, or quality of life in the coenzyme Q10 group . Creatine has been studied in NMD because it increases skeletal muscle mass in healthy exercising individuals and also reduces ATP loss during heavy anaerobic exercise by supplying more phosphocreatine to the muscle . However, there have been mixed results in NMD, as it seems cause a significant increase in strength in muscular dystrophy patients compared with placebo, but not in metabolic myopathies …”

Section: New Approaches To Exercise Training In Nmdmentioning

confidence: 99%

Exercise in neuromuscular disease

Anziska

Sternberg

2013

Muscle and Nerve

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In this review, we present an overview of the role of exercise in neuromuscular disease (NMD). We demonstrate that despite the different pathologies in NMDs, exercise is beneficial, whether aerobic/endurance or strength/resistive training, and we explore whether this benefit has a similar mechanism to that of healthy subjects. We discuss further areas for study, incorporating imaginative and novel approaches to training and its assessment in NMD. We conclude by suggesting ways to improve future trials by avoiding previous methodological flaws and drawbacks in this field.

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Section: New Approaches To Exercise Training In Nmdmentioning

confidence: 99%

Exercise in neuromuscular disease

Anziska

Sternberg

2013

Muscle and Nerve

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“…Furthermore, one may expect more extensive research with follow-up in a non-life-limiting condition. With regard to postpolio syndrome, despite a number of intervention trials [28][29][30][31][32][33] , the lack of reported incidence/prevalence may reflect difficulties in confirming diagnoses due to the symptoms being similar to those associated with natural ageing. Accurate case ascertainment would be difficult and expose statistics to bias.…”

Section: Non-reported Conditionsmentioning

confidence: 99%

A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK

Hoppitt¹,

Pall

Calvert³

et al. 2010

Neuroepidemiology

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Background: Updated, robust estimates of the incidence and prevalence of rare long-term neurological conditions in the UK are not available. Global estimates may be misrepresentative as disease aetiology may vary by location. Objectives: To systematically review the incidence and prevalence of long-term neurological conditions in the UK since 1988. Search Strategy: Medline (January 1988 to January 2009), Embase (January 1988 to January 2009), CINAHL (January 1988 to January 2009) and Cochrane CENTRAL databases. Selection Criteria: UK population-based incidence/prevalence studies of long-term neurological conditions since 1988. Exclusion criteria included inappropriate diagnoses and incomprehensive case ascertainment. Data Collection and Analysis: Articles were included based on the selection criteria. Data were extracted from articles with ranges of incidence and prevalence reported. Main Results: Eight studies met the criteria (3 on motor neurone disease; 4 on Huntington’s disease; 1 on progressive supranuclear palsy). The incidence of motor neurone disease ranged from 1.06 to 2.4/100,000 person-years. The prevalence ranged from 4.02 to 4.91/100,000. The prevalence of Huntington’s disease ranged from 4.0 to 9.94/100,000. The prevalence of progressive supranuclear palsy ranged from 3.1 to 6.5/100,000. Conclusions: The review updates the incidence/prevalence of long-term neurological conditions. Future epidemiological studies must incorporate comprehensive case ascertainment methods and strict diagnostic criteria.

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“…Muscle strength, muscle endurance and quality of life increased statistically significantly in all 14 patients but there was no significant difference between the CoQ 10 and placebo groups (Kough et al, 2008).…”

Section: Average Daily Intake Through Diet = 3 To 5 Mg (Webermentioning

confidence: 81%

Coenzyme Q₁₀: multiple benefits in one ingredient

Littarru

Lambrechts

2011

OCL

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Effects of resistance training in combination with coenzyme Q10 supplementation in patients with post-polio: a pilot study

Abstract: There was no effect of coenzyme Q10 supplementation during resistance training on post-polio syndrome symptoms. Thus, supplementation with coenzyme Q10 has no beneficial effect on muscle function in patients with post-polio syndrome.

Cited by 34 publications

References 6 publications

Exercise in neuromuscular disease

Exercise in neuromuscular disease

A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK

Coenzyme Q₁₀: multiple benefits in one ingredient

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Effects of resistance training in combination with coenzyme Q10 supplementation in patients with post-polio: a pilot study

Abstract: There was no effect of coenzyme Q10 supplementation during resistance training on post-polio syndrome symptoms. Thus, supplementation with coenzyme Q10 has no beneficial effect on muscle function in patients with post-polio syndrome.

Cited by 34 publications

References 6 publications

Exercise in neuromuscular disease

Exercise in neuromuscular disease

A Systematic Review of the Incidence and Prevalence of Long-Term Neurological Conditions in the UK

Coenzyme Q10: multiple benefits in one ingredient

Contact Info

Product

Resources

About

Coenzyme Q₁₀: multiple benefits in one ingredient