1991
DOI: 10.1097/00000542-199103000-00014
|View full text |Cite
|
Sign up to set email alerts
|

Effects of Residual Concentrations of Isoflurane on the Reversal of Vecuronium-induced Neuromuscular Blockade

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

4
26
0
1

Year Published

1994
1994
2014
2014

Publication Types

Select...
5
3

Relationship

0
8

Authors

Journals

citations
Cited by 53 publications
(31 citation statements)
references
References 0 publications
4
26
0
1
Order By: Relevance
“…Measurements of T1 ⁄ control and train-of-four ratio (TOFR) were taken 3 min, 6 min, 9 min, 12 min and 15 min after the administration of neostigmine, and the values for the two groups were compared. It has been shown that 15 min after the administration of neostigmine at a T1 ⁄ control value of 0.25, TOFR often does not return to 0.9 [14][15][16][17].…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Measurements of T1 ⁄ control and train-of-four ratio (TOFR) were taken 3 min, 6 min, 9 min, 12 min and 15 min after the administration of neostigmine, and the values for the two groups were compared. It has been shown that 15 min after the administration of neostigmine at a T1 ⁄ control value of 0.25, TOFR often does not return to 0.9 [14][15][16][17].…”
Section: Methodsmentioning
confidence: 99%
“…Further, it has been postulated that if neostigmine 40 lg.kg )1 is administered when T1 ⁄ control = 0.25, TOFR returns to a value of 0.9 after about 15 min [14][15][16]. For this reason, recovery from neuromuscular blockade was studied for 15 min after neostigmine administration in this study.…”
mentioning
confidence: 96%
“…1 In our study also, the reversal was slowed in the presence of sevoflurane, and to some extent isoflurane anesthesia, and in some patients the block had not reversed even by 30 min. However, when the volatile agent administration was discontinued at the time of neostigmine administration, the reversal times were not different from the propofol groups.…”
Section: Discussionsupporting
confidence: 55%
“…REVIOUS studies have shown that antagonism of block with relaxants such as vecuronium is impeded in the presence of potent volatile agents such as sevoflurane and isoflurane. [1][2][3] It has also been shown that sevoflurane anesthesia potentiates the effect of rocuronium compared with isoflurane and propofol anesthesia. 4 Although there are reports of antagonism of rocuronium block with neostigmine, these have generally examined the influence of the dosage or the timing of administration of the anticholinesterase.…”
mentioning
confidence: 99%
“…Addition of 1 MAC isoflurane was found to decrease the T4/Tt values by 10-15%. 21 In the present study, approximately 0.4 MAC isoflurane was used, and the results are between those obtained with nitrous oxide-narcotic and nitrous oxide-isoflurane anaesthesia. 2j The effect of neostigmine given at the same twitch height recovery was the same in Montrtal and in Paris.…”
Section: Discussionmentioning
confidence: 56%