Effects of quazepam as a preoperative night hypnotic: comparison with brotizolam

Nishiyama, Tomoki; Yamashita, Koichi; Yokoyama, Takeshi; Imoto, Akinobu; Manabe, Masanobu

doi:10.1007/s00540-006-0445-2

Cited by 2 publications

(2 citation statements)

References 17 publications

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“…Midazolam also reduces dream recall as compared with propofol ( 114 ). Finally, taking quazepam or brotizolam the night before a surgery reduces the number of dreams recalled while increasing the duration and quality of sleep ( 115 ).…”

Section: Effects Of Anxiolytic and Hypnotic Drugs On Dream Recallmentioning

confidence: 99%

Dreams, Sleep, and Psychotropic Drugs

Nicolas

Ruby

2020

Front. Neurol.

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Over the past 60 years, the impact of psychotropic drugs on dream recall and content has been scarcely explored. A review of the few existing experimental results on the topic leads us to the following conclusions. For antidepressant drugs, in the great majority, they reduce dream recall frequency (DRF), and the improvement of depressive symptoms is associated with an increase of positive emotion in dream content. For sedative psychotropic drugs, their improvement of sleep quality is associated with a reduction of DRF, but the effect on dream content is less clear. Few occurrences of nightmare frequency increase have been reported, with intake of molecules disturbing sleep or with the withdrawal of some psychotropic drugs. Importantly, the impact of psychotropic drugs on rapid eye movement (REM) sleep does not explain DRF modulations. The reduction of intra-sleep awakenings seems to be the parameter explaining best the modulation of DRF by psychotropic drugs. Indeed, molecules that improve sleep continuity by reducing intra-sleep awakenings also reduce the frequency of dream recall, which is coherent with the "arousal-retrieval model" stating that nighttime awakenings enable dreams to be encoded into long-term memory and therefore facilitate dream recall. DRF is nonetheless influenced by several other factors (e.g., interest in dreams, the method of awakening, and personality traits), which may explain a large part of the variability of results observed and cited in this article.

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Section: Effects Of Anxiolytic and Hypnotic Drugs On Dream Recallmentioning

confidence: 99%

Dreams, Sleep, and Psychotropic Drugs

Nicolas

Ruby

2020

Front. Neurol.

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“…As surgery is one of the most stressful events physically and mentally, it could be associated with sleep disturbances [6,7]. Murphy et al [5] performed a survey examining perioperative sleep patterns in 110 in-hospital patients who were admitted for abdominal surgery.…”

Section: Introductionmentioning

confidence: 99%

A pragmatic evaluation of sleep patterns before gynecologic surgery

et al. 2010

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The aim of this study was to evaluate preoperative sleep patterns in-patients scheduled for elective endoscopic surgery and to compare sleep characteristics before different types of endoscopic procedures. A prospective survey cohort study (Canadian Task Force classification II-2) was designed to evaluate quantitative and qualitative (score 1-7) sleep parameters. Patients completed sleep-monitoring forms on the baseline (6 weeks before surgery), two nights (night-2), and the night before surgery (night-1). Of a total 119 women, 73 (61%) underwent laparoscopies and 46 (39%) hysteroscopies. Forty-seven (40%) operations involved organ removal and 72 (60%) were reconstructive surgery. The mean overall sleep-quality score on night-1 (3.29±0.15) was higher (worse) than on baseline (2.09±0.10, P<0.0001) and night-2 (2.45±0.11, P<0.001, respectively). Patients reported more difficulty falling asleep on night-1 (2.53±0.15) than on baseline (1.61±0.09, P<0.0001) and night-2 (1.84±0.12, P=0.001, respectively). The mean number of nocturnal awaking events was also highest on night-1 (1.52±0.17) than on baseline (0.69±0.09, P<0.001) and night-2 (0.87±0.09, P< 0.05 respectively). Using logistic regression, we found that age, stress level, and time before surgery (baseline, night-2, night-1), were significant predictors of poor sleep. The type of planned surgery did not influence the quality of sleep. Falling asleep on night-1 took longer than on baseline and night-2. There was no difference in the sleep quality measures between the baseline and night-2. Poor sleep quality is common mainly in the night before surgery. The nature and extent of planned surgery do not affect sleep quality variables.

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Effects of quazepam as a preoperative night hypnotic: comparison with brotizolam

Abstract: The preoperative night hypnotics, quazepam and brotizolam improved sleep before surgery. As a preoperative night hypnotic, quazepam 30 mg and 45 mg increased the total duration of sleep compared to brotizolam 0.25 mg.

Cited by 2 publications

References 17 publications

Dreams, Sleep, and Psychotropic Drugs

Dreams, Sleep, and Psychotropic Drugs

A pragmatic evaluation of sleep patterns before gynecologic surgery

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