Effects of propylene glycol drenching on energy balance, plasma glucose, plasma insulin, ovarian function and conception in dairy cows

Effects of propylene glycol drenching before and after luteolysis on blood glucose, ovarian steroids and follicular dynamics in heifers

“…Under such metabolic conditions induced by administration of oral propylene glycol drenching that was adapted for ketosis therapy, no significant effect on ovarian function such as follicular growth and the development of corpus luteum was observed after the treatment. Previous study reported that long-term treatment with propylene glycol promoted the onset of first post-partum ovulation in dairy cows (Miyoshi et al, 2001;Chagas et al, 2007). In contrast, the present results appear to support another observation in dairy cows that post-partum ovarian dynamics and the first ovulation were not influenced by the treatment of propylene glycol (Rizos et al, 2008).…”

“…Some previous studies showed a rise of blood glucose concentration in dairy cows given propylene glycol orally (Studer et al, 1993;Grummer et al, 1994;Miyoshi et al, 2001;Rizos et al, 2008). In contrast, others did not observe any changes in blood glucose concentration after propylene glycol administration (Chagas et al, 2007;Moallem et al, 2007).…”

“…A previous -E-mail: tomomit@cc.tuat.ac.jp study showed that propylene glycol drenching for 35 days during the period of early lactation increased blood levels of glucose and insulin, and decreased NEFA level in dairy cows (Miyoshi et al, 2001). Moreover, in that study, propylene glycol treatment to dairy cows under the condition of negative energy balance shortened the duration between parturition and first post-partum ovulation (Miyoshi et al, 2001), suggesting that the long-term supplementation of propylene glycol may have positive influences on follicular function via the stimulation of glucose availability in postpartum dairy cows.…”

Effect of dietary energy source on energy balance, production, metabolic disorders and reproduction in lactating dairy cattle

“…On the contrary, 22 out of 31 studies [8, 9, 15, 60, 61, 63-65, 67, 68, 78, 82, 99-107] reported a decrease in DMI after feeding extra lipogenic nutrients compared to 7 out of 14 studies [60,61,68,72,77,78,[108][109][110][111][112][113][114][115][116] on extra glycogenic nutrients which showed a decrease in DMI in the treatment group. In general, the negative effect of extra lipogenic sources on dry matter intake is higher when the degree of saturation of fatty acids is lower, probably because of the more pronounced negative effects of unsaturated fatty acids on rumen carbohydrate fermentation.…”

“…Eight of the 12 studies reported an increase in EB after feeding extra lipogenic nutrients [8, 9, 12, 15, 64,66,106]. In contrast to feeding extra glycogenic nutrients where 12 out of 13 studies were able to improve, not-significantly, the calculated EB [66,69,71,72,77,107,108,110,112,116,120].…”