Effects of prolonged exposure to 4-tert-octylphenol on toxicity and indices of oestrogenic exposure in the sand goby (Pomatoschistus minutus, Pallas)

Robinson, Craig D.; Brown, Elaine; Craft, John A.; Davies, Ian; Moffat, Colin F.

doi:10.1016/j.marenvres.2003.12.001

Cited by 17 publications

(9 citation statements)

References 58 publications

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“…Secondary sexual characteristics, such as male nuptial coloration or urogenital papilla development, are hormonally controlled in fish (Kirby et al, 2003;Brion et al, 2004;Robinson et al, 2004). A number of these morphological characteristics are specific only to males and include breeding tubercles (occur in many cyprinid fish), fat pad (in mature male fathead minnows), and a modified anal fin (gonopodium in the mosquitofish and guppy) (Brion et al, 2004).…”

Section: Discussionmentioning

confidence: 99%

“…A number of these morphological characteristics are specific only to males and include breeding tubercles (occur in many cyprinid fish), fat pad (in mature male fathead minnows), and a modified anal fin (gonopodium in the mosquitofish and guppy) (Brion et al, 2004). These all developed as the male fish becomes sexually mature ( Robinson et al, 2004). Secondary sexual characteristics of fish can be manipulated through exposure to pollutants .…”

Section: Discussionmentioning

confidence: 99%

“…No other reference could be found where the UGPLI was used to indicate EDC exposure in fish collected in the field. Robinson et al(2003) and Robinson et al (2004) did, however, make use of this index to indicate EDC effects in laboratory studies of P. minutus exposed to EE2 and a sewage effluent (containing APnEOs), and OcP respectively. The exposure to EE2 and the sewage effluent resulted in the impairment of male UGP development and the exposure to OcP resulted in the morphological feminization of the male UGPs.…”

Section: Discussionmentioning

confidence: 99%

“…These include exposure studies done on Danio rerio (zebrafish) (Brion et al, 2004); Etheostoma caeruleum (rainbow darter) (Elias et al, 2007); Lythrypnus dalli (bluebanded goby) (Kirby et al, 2003); Oryzias latipes (Japanese medaka) (Yamamato and Suzuki, 1955;Parrott et al, 2003), and exposed or wild collected specimens of Pomatoschistus minutus. (sand goby) (Matthiessen et al, 2002;Kirby et al, 2003;Robinson et al, 2003;Robinson et al, 2004;Rodrigues et al, 2006). Results obtained indicated that the UGP can be a useful bioindicator of EDC exposure due to alterations in the structures.…”

Section: Introductionmentioning

confidence: 93%

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The use of the urogenital papillae of male feral African sharptooth catfish (Clarias gariepinus) as indicator of exposure to estrogenic chemicals in two polluted dams in an urban nature reserve, Gauteng, South Africa

Kruger

Barnhoorn

Vuren

et al. 2013

Ecotoxicology and Environmental Safety

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The use of the urogenital papillae of male feral African sharptooth catfish (Clarias gariepinus) as indicator of exposure to estrogenic chemicals in two polluted dams in an urban nature reserve, Gauteng, South Africa AbstractThe African sharptooth catfish (Clarias gariepinus) is indigenous to South Africa where it is commonly found in calm waters such as lakes, streams, rivers, swamps and floodplains. The males of this gonochoristic species can be readily distinguished from females via a distinct elongated urogenital papilla with a pointed tip, located just behind the anus. This structure is an androgen controlled secondary sexual characteristic and could potentially be affected by chemicals displaying endocrine disrupting properties during development. Results of previous studies on effects on papillae of different fish species indicated that these structures could be useful as bio-indicators of exposure due to alterations in the structures. This study investigated the occurrence of abnormal morphology in urogenital papillae compared to the macroscopic and microscopic structure of the gonads of presumed male or intersex catfish sampled from the Rietvlei and Marais dams in an urban nature reserve, due to exposure to endocrine disrupting chemicals (EDCs). Macroscopic observation of the UGP, gonad examination after laparotomy and histology were done. Gonadosomatic index (GSI) and Urogenital papilla length index (UGPLI) were determined for all fish collected. Mesenteric fat analyzed for selected alkylphenols and organochlorines showed high levels of especially nonylphenol indicating long term exposure to these chemicals due to bio-accumulation. The GSI indicated that fish with intersex gonads were probably feminized males. It was concluded that use of the UGP alone, without macroscopic and microscopic analyses of the gonads, could not effectively indicate exposure to EDCs.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 93%

See 2 more Smart Citations

The use of the urogenital papillae of male feral African sharptooth catfish (Clarias gariepinus) as indicator of exposure to estrogenic chemicals in two polluted dams in an urban nature reserve, Gauteng, South Africa

Kruger

Barnhoorn

Vuren

et al. 2013

Ecotoxicology and Environmental Safety

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“…Alkylphenols are observed to be estrogenic in fish both in vivo and in vitro (Madsen et al, '97;Christiansen et al, '98;Andreassen and Korsgaard, 2000;Rasmussen et al, 2002;Robinson et al, 2004).…”

mentioning

confidence: 99%

Effects of exposure to the xenoestrogen octylphenol and subsequent transfer to clean water on liver and gonad ultrastructure during early development of Zoarces viviparus embryos

et al. 2010

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Female eelpouts (Zoarces viviparus L.) are exposed during early pregnancy to nominal concentrations of 100 microg/L of 4-tert-octylphenol (OP) or 0.5 microg/L of 17beta-estradiol (E2). Effects on maternal metabolism and on liver and gonad development in embryos were examined and compared with controls (C) during exposure and after transfer to clean water (depuration). In the mother fish, significantly higher concentrations of plasma vitellogenin (vtg) and calcium were found in the two exposed groups, when compared with the C group after exposure and depuration. When compared, however, with the respective values after exposure, vtg had decreased significantly after depuration. The hepatosomatic index was normalized after depuration. In both exposed groups, the hepatocytes were rounded and not distinctly polygonal as in the controls. The amount of glycogen was considerably less while the number of mitochondria increased, and the rER significantly proliferated after exposure as well as after depuration. The gonads of nine of more than 28 embryos in the group treated with OP exhibited a number of abnormalities as compared with the normal gonad development in both sexes. Feminization of the male gonads in the exposed specimens and a number of histopathological features were observed in all the abnormal gonads, whereas reliable male features, such as formation of seminiferous tubules or spermioduct, were not observed. This study showed that 4t-tert-OP and 17beta-estradiol exert estrogenic effects during very early development of the embryos and that depuration had a positive effect on the motherfish and her embryos.

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Molecular Cloning and Induction of Vitellogenesis

Abinaya,

Baskaralingam

2023

Vitellogenin in Fishes- Diversification, Biological Properties, and Future Perspectives

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Effects of prolonged exposure to 4-tert-octylphenol on toxicity and indices of oestrogenic exposure in the sand goby (Pomatoschistus minutus, Pallas)

Cited by 17 publications

References 58 publications

The use of the urogenital papillae of male feral African sharptooth catfish (Clarias gariepinus) as indicator of exposure to estrogenic chemicals in two polluted dams in an urban nature reserve, Gauteng, South Africa

The use of the urogenital papillae of male feral African sharptooth catfish (Clarias gariepinus) as indicator of exposure to estrogenic chemicals in two polluted dams in an urban nature reserve, Gauteng, South Africa

Effects of exposure to the xenoestrogen octylphenol and subsequent transfer to clean water on liver and gonad ultrastructure during early development of Zoarces viviparus embryos

Molecular Cloning and Induction of Vitellogenesis

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