Effects of processing on the mineral content, proximate composition and phytochemical factors of the seeds of bauhinia monandra (kurz)

Agbugui, M. O.; Oniye, S. J.; Auta, J.

doi:10.4314/bajopas.v3i1.58558

Cited by 5 publications

(7 citation statements)

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“…The results of the minerals composition Table (4), showed the mineral composition Senna occidentalis Root, high concentrations values were found in potassium (43 mg/l or ppm) followed by phosphorous (28.5 mg/l), calcium (15 mg/l), sodium (3.65 mg/l) and magnesium (0.145mg/l). Similar ndings were reported by Agbugui,, et al [40]. In the other species of the same family.…”

Section: Physiochemical Anaylsissupporting

confidence: 91%

Physiochemical, Insecticidal and Antidiabetic activities of Senna occidentalis Linn Root

Issa

Ahmed

Mohamed

et al. 2020

Preprint

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The present study aimed to investigate the physiochemical activities of Senna occidentalis (Linn) roots, phytochemicals as insecticidal (ethyl acetate and methanol) and antidiabetic (ethanolic extract) activities. Physicochemical properties were carried out by using Association of Official Analytical Chemists methods, thin layer chromatography was carried out according to the Stahl method. Larvicidal activity and LD50 were studied against third instar of Culex quinquefasciatus mosquito larvae to detect, which extract is safe or toxic. The ethanolic extracts of the roots were orally tested at the dose 200 mg/kg for hypoglycemic effect on induced hyperglycemia in normal rats, assessed in the ethanol extract were compared with diabetic control and standards Glibenclamide 10mg/kg. Physiochemical parameters showed high parameters in nitrogen free extract (69.6%), curd fiber (14.5%), crude proteins (8.15%), ether extract (3.75%), and both Ash and moisture (2%), high concentrations values were found in potassium (43 mg/l) followed by phosphorous (28.5 mg/l), calcium (15 mg/l), sodium (3.65 mg/l) and magnesium. (0.145 mg/l) in this part beside phytochemical compounds showed high amount of alkaloids, triterpene, flavonoids, tannins, sugars, and few amount of Anthraquinone glycosides. Thin layer chromatography (TLC) studies different colored phytochemical constituted with different Rf values. All the spots are colored under UV light, but some are localized colorless after spaying. Ethyl acetate (EtAc) extract showed eight spots and methanol (MeOH) extract showed thirteen spots. The Larvicidal activity showed that ethyl acetate extract was safe against mosquito larvae with LD50 value 1412.54 (p<0.05) and methanol extract had moderate larvicidal activity against mosquito larvae with LD50 value 257.54 (p<0.05). While the ethanolic extract of Senna occidentalis (L.) cause a favorable hypoglycemic activity when compared to control significant reduction by [53.15%, 32.87% and 20.94%] respectively as while as standard Glibenclamide. Based on the various data of the physicochemical parameters, TLC spots and phytochemical compounds of Senna occidentalis root, they could be used as references standards for manufacturing units of Senna occidentalis root Larvicidal and antidiabetic drugs.

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Section: Physiochemical Anaylsissupporting

confidence: 91%

Physiochemical, Insecticidal and Antidiabetic activities of Senna occidentalis Linn Root

Issa

Ahmed

Mohamed

et al. 2020

Preprint

View full text Add to dashboard Cite

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“…Several studies have been conducted on the pharmacological activities of B. monandra extracts (Argolo et al, 2004;Macedo, 2008;Agbugui et al, 2010;Starr and Starr, 2011;Ajiboye et al, 2015), but no study was conducted on the effect of the B. monandra extract on platelet augmentation or to analyze its hematopoietic potential. However, a previous report revealed that a high content of iron in the extract may assist blood formation (Agbugui et al, 2010). Moreover, previous studies have also reported the use of other plants in platelet augmentation (Osime et al, 2008;Arollado and Osi, 2010;Apostol et al, 2012;Arollado et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

“…In the Yoruba tribe of South Western Nigeria, it is called "Abafe" (Ajiboye et al, 2015), and its decoction is taken to improve blood function, which is one of its health benefits. The tree is also fairly widely distributed throughout the natural grassland of Northern and South Eastern Nigeria (Agbugui et al, 2010). The leaf extract is bitter and traditionally used for the treatment of diabetes in Nigeria, Brazil (McCune and Johns, 2002), and Asia (Macedo, 2008).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of antidote potential of methanol leaf extract of Bauhinia monandra on heparin-induced thrombocytopenia in mice

Nworie¹,

Okorie²,

Ebere³

et al. 2019

bta

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Thrombocytopenia is closely associated with heparin therapy and hematological disorders and other common diseases in patients admitted in the hospital. Globally, thrombocytopenic cases in hospitals leading to 80% of deaths are mainly due to refractory bleeding and lack of availability of platelet concentrates. Currently, chemical compounds for managing thrombocytopenia are needed. The aim of the study was to determine the effect of methanolic leaf extract of Bauhinia monandra as a potential antidote for treating heparin-induced thrombocytopenia (HIT). A total of 30 mice were used for the experimental study. The mice were divided into five Groups (I-V) of six mice each. Group I (normal control) was given distilled water only, and Group II (positive control) was given heparin only. Groups III, IV, and V (treatment groups) were given heparin and methanolic leaf extract of B. monandra at a dose of 100, 200, and 400 mg/kg body weight (b. wt), respectively. Furthermore, blood samples were collected to determine the blood platelet count. Bleeding time and clotting time were also determined. This study showed that the mice in the group treated with methanolic leaf extract of B. monandra at a dose of 400 mg/kg b. wt had significantly (P < 0.05) higher platelet counts (225.10 ± 6.41) than the control groups: normal control (181.90 ± 11.38) and positive control (127.65 ± 5.79). It also significantly decreased the bleeding and clotting time. Acute toxicity test showed no significant physical and behavioral changes. The results from this study show that leaf methanolic extract of B. monandra is effective as an antidote for treating HIT.

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Section: Introductionmentioning

confidence: 99%

“…The plant Bauhinia monandra is a leguminous tree with large leaves and pink flowers with red dots (Agbugui et al, 2010), commonly used in ornamental gardens (Anhwang et al, 2005), as nutritional source of vitamin A (Balogun & Fetuga, 1985) and in application to forage (Ilkiu-Borges & Mendonça, 2009). This plant is in general found in West Africa and India (Agbugui et al, 2010;Anhwang et al, 2005), but it also can be found in South America, especially in Brazil where it is indicated among other uses as a natural antidiabetic medicine (Menezes et al, 2007;Macêdo et al, 2008). According to studies disclosed in the literature, the utilization of Bauhinia monandra as well as several other species of this genus (Silva & Cechinel-Filho, 2002) as a hypoglycemic agent was possible because of the presence of flavonoids, such as a glycones or glycosides, which have been isolated from Bauhinia species (Cechinel-Filho, 2009;Menezes et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Constituents Isolated from the Stem Bark of Bauhinia monandra

2018

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The methanolic extract from stem bark of Bauhinia monandra, a medicinal plant employed in folk medicine, yielded by column chromatography lup-20(29)-en-3β,24-diol (1) and methyl galloate (2) along with β-sitosterol (3). These known phytoconstituents are being reported for the first time from this plant and their structures were established by NMR and MS spectral studies and by comparison with their literature data. Furthermore, lup-20(29)-en-3β,24-diol (1), a minor constituent, was isolated from this genus for the first time.

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Effects of processing on the mineral content, proximate composition and phytochemical factors of the seeds of bauhinia monandra (kurz)

Abstract: ABSTRACT

Cited by 5 publications

References 5 publications

Physiochemical, Insecticidal and Antidiabetic activities of Senna occidentalis Linn Root

Physiochemical, Insecticidal and Antidiabetic activities of Senna occidentalis Linn Root

Evaluation of antidote potential of methanol leaf extract of Bauhinia monandra on heparin-induced thrombocytopenia in mice

Phytochemical Constituents Isolated from the Stem Bark of Bauhinia monandra

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